Oxycontin not working after one hour.

I've searched for this topic, but can find no post on this particular problem. I have been taking Oxycontin 10mg for a year. Just recently, I find that my nighttime dose "fails" after about one hour. If I take 500mg of Paracetamol ( Acetaminophen ) , relief comes back within 30 minutes and lasts until morning.
I avoid alcohol and grapefruit etc.
Does anyone else experience this and why could it be happening?
Apologies if this has come up already and thanks for any answers.

Madiegs:
I agree with Susie that I would query your pharmacist and see if your latest prescription was filled with a different generic manufacturer’s tablet.

Generic medications only have to be “chemically equivalent” to one another. One generic prescription medication may have more or less filler and more or less active ingredient. The variation can be as wide as 5%. All generic medications are not equal in potency of active ingredient or in the quality of input ingredients.

I have had the experience of taking a brand of generic prednisone that seemed like it was taking a placebo. I talk with my pharmacist and learns that the particular generic manufacturer had a reputation for low quality practices. He now routinely fills my prescription with a generic prednisone that has a higher quality standards.

Tossing out thoughts and ideas . . . .

The other consideration is a possible interaction effect either with another prescription medication that you are taking or with a supplement.

A last consideration would be that you have acquired a physiological tolerance to OxyContin 10 mg. Your body has become accustomed to and sensitized to a minimal amount of opiate in your bloodstream. A 10 mg dose will have a lower/lessened effect or presence for you and your body’s current state of being.

Sending you a dose of understanding,
Karen

ML, although the ER medications are designed to last 12 hours, reality is they don't. Many find the 8 hour mark is about the normal. We all metabolize our medications differently. My thoughts are you are not becoming tolerant to the medication. I think its great that you can take the acetaminophen helps kick start it.

No, Healing Well does not have a separate forum for restless legs. However, you are more than welcome to post here about it. Many years ago I had restless leg & it just came out of no where. I would wake myself up kicking in the middle of the night. My dr put me on Mirapex & that really helped. He also had me massage my legs & feet. Are you on any medication for this? I stayed on Mirapex for a couple of years & decided to stop taking it to see what would happen. As it turned out I did not need to go back on it. It apparently left just like it appeared. My husband is diabetic & let me tell you he kicks & twitches all night long. It is common for diabetics to get this.

Take care.