I've been on prednisone constantly for almost two years now. It caused my vision to worsen the first year and a half, but it's stayed stable the last 6 months. I have recently gained some weight, but that's because I used to work out
a lot and had to stop working out completely due to arthritis issues. So, other than vision changes, I've had no side effects...no moon face, buffalo hump, moodiness (no more so than normal
![:-)](/community/emoticons/smile.gif)
). It really does help me but I've gotten to where I am physically dependent on it for the arthritis. Dr. has tried to get me off of it many times, but nothing else works enough to be able to do that without the flare getting worse.