I started Effexor XR about
a year ago, starting at 37.5 mg. It does have a stimulating effect so I always take it in the morning, usually around 10AM. I had never used any other anxiolytic or antidepressant before in my life, however I was (and still am) fighting cancer, and when my wife was also diagnosed she became hostile and everything just became overwhelming.
The only side effects I recall early on was a constant headache which eventually disappeared after a few weeks, and a hissing sound in my head (not auditory tinnitus) that still persists today. Searching other MDD forums I found others who had experienced the buzzing noise also. That early small dosage got me thru a couple difficult surgeries. Fairly soon thereafter I upped my dose to 75MG which has helped to counteract some of the SE's of chemo.
There are times I feel myself slipping and in January upped my dose to 150mg again in AM. It's hard to keep a positive outlook and I still have crying fits that can last for hours. My Dr said I can go as high as 300mg, but recently tried 225 per day for a week or so and the buzzing in my head became unbearable and it didn't do much to help the moodiness so I'm sticking with 150mg.
I don't remember ever feeling spaced out at any time, even initially, but the first couple months I was relieved to have found something that worked. Anyway, the discontinuation syndrome is real. I was sick with dry heaves a few weeks ago and couldn't take anything for a day, and could feel the brain shoops starting already just missing one day. Now it seems it's not working so well anymore, which surprised me as I'd heard it has good durability. Getting off this stuff will be difficult. I've heard it's worse than narcotic withdrawal.
I'm hoping as you posted a while ago that you've either become accustomed to the drug or found something else that works.
Post Edited (RobLee) : 4/15/2018 6:55:52 AM (GMT-6)