Don’t know what to do... pristiq, Rexulti, Wellbutrin

My Dr. had me try Cymbalta. I was on Pristiq. The Cymbalta caused GI and sleep problems. We went back to Pristiq. I’ve been on 50mg for a month and on 100 mg for 31 days. In full blown depression and Pristiq is now not helping at all. In the past it started helping after just 1 week. Dr. Added Wellbutrin 2 weeks ago. It’s causing me to have increased pain. (I have Lyme disease). So now I’m depressed and in constant pain. She wants me to add Rexulti. After reading info and reviews, I’m really freaked out to try it. The list of side effects is super long and most people seem to gain quite a bit of weight. Christmas is 2 weeks away and I’m dying to feel better! What are your thoughts on Rexulti.

Only other med I have been on is Zoloft and I felt great on it. Went off of it when I was pregnant. When I went back on it, it didn’t work. It seems like when I stop a med and go back on it a few months later, it no longer works.

I feel like I haven’t tried so many meds. That maybe I should try other meds before taking the Rexulti?

Really don’t want to gain weight. My hubby is bipolar and has been manic for quite some time and became obsessed with triathlons and is in great shape. I need to lose like 40lbs. I don’t want to gain anymore... it will affect my marriage.

Just don’t know what to do...

Hello Inspired

I was on Cymbalta it worked well for me on depression, had to take with food, as it caused nausea
had to switch to Effexor as my insurance only pays for generic when there is one. The generic Cymbalta did not help me.

Effexor works for me along with lamictal. A lot of people need a combo of meds, depression and mood stabilizer.

I am so sorry that weight will effect your marriage. I can empathize with that. My husband was always over weight. We were married 30yrs. I have other diagnosis's medical. I have gained 30 lbs from wedding weight.

3years ago he went on some diets program, lost 85lbs. found a 35 yr woman, he is 60. We have been separated for 2.5 years. Devastated at first, then found out I was never really loved for me!. I am much happier now on my own.

Of course you are not me and I have no idea about your relationship.

I hope this helps.

Peace and strength
Trina

I

It is most important to feel well mentally. Once you start feeling better you become more active and you start to lose weight.

I didn't gain weight on abilify until I went up to 20mg. I started out at 5mg. I think I gained a total of 8 pounds. But I have since lost it. Then gained weight on Lexapro. I am staying on a low dose.

It is winter though and I always gain a little during the holidays. Plus I am not out walking daily.

Take care of your mental health. Your husband will love you no matter what. I do know how you feel but I really think once you get to feeling better that the weight will come off. Plus when we are depressed we see ourselves as unattractive. Even though we aren't.

Have a good day...

Hugs, Karen...