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Trintellix AKA Brintellix

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Depression
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Posted 4/11/2015 2:21 PM (GMT -5)
I am new to this site... in fact I've never been on a chat forum like this before. I am feeling very lost today and don't know where to turn due to my desire to keep my feeling of helplessness away from my family and friends.

I have been on antidepressants for most of my adult life. Overall, I'm a positive person (outwardly) but inside I feel like I'm not smart and worthless. My memory is failing me to the point I worry if I have something much bigger going on and I'm terrified I am going to lose my job. My doctor said the symptoms are classic for someone who suffers with depression but the Cipralex doesn't seem to be working for my cognitive and memory function. She gave me 10mg of Trintellix to take for 2 weeks, then 20mg after that. I started taking it 3 days ago and the first day I felt extremely agitated. That went away on day 2 but I have been tired and very weepy for the last couple of days. Granted I have had some enormous changes in my life and I feel like I am only starting to REALLY grieve the changes now. I am really hoping that the sadness I have goes away, that my focus and memory will come back and that I can start to enjoy the good things in my life in less sporadic ways.

Can anyone tell me about their experiences with this drug?
Posted 4/11/2015 3:26 PM (GMT -5)
Hi Seeking Peace,

Welcome to the depression forum. We do have a chat room too, I hear that there are more people in it during the evenings.

I have never tried Trintelix, or Brintellix. I have been taking pristiq for a few years and before that I took Effexor for many years. I have been on antidepressants for probably 26 years or so. Not positive about that.

With many (as you probably know) antidepressants, there are unpleasant side effects in the beginning. We always hope that will go away and usually does in a week or two. Seems like there are many that make you feel more depressed at the beginning. I am sorry that you are going though this. The agitation is no fun at all.

I try to do puzzles and such to help my memory. It seems that (and I am not sure how to spell this) Ginko Biloba is good for the memory. It is an herb. But working the mind helps a lot. Mindfulness can help with this too. If you are interested there is a site called "mindful.org" that you can go to and work on that. I hear it is very good. I practice mindfulness and meditation daily. They both help me.

Do you journal? Journaling helps a lot to. You could write down the side effects and what day. You will have that to look back on. But writing down things every day is good. Especially things that we are thankful for. It makes us feel better.

There are many coping skills that you can learn. Go to the first thread on the forum called Depression Resources. It has a lot of helpful information.

I hope you feel better soon. Keep posting, it does help to know you aren't alone.

Hugs, Karen...
Posted 4/12/2015 2:18 AM (GMT -5)
I tried Brintellix but it didn't seem to do anything for me. I'm on Fetzima, Wellbutrin and Abilify now and I still feel like I'm not doing as well as I could be. I hope that the Brintellix will work for you. I worry about my memory sometimes too. It seems to get worse when I'm under a lot of stress. I like to play an app called "Brain Games" on my phone, i'm Hoping that will help some.. not sure if it does but what the heck. Anyway.. hang in there.. eventually something should work.
Posted 4/12/2015 4:27 AM (GMT -5)
Solitare!!!! that's my brain game. try the puzzles that joyce does on the forum. meds are hit and miss. trial and error. support is key. keep strong.
Posted 9/2/2016 9:04 PM (GMT -5)
I'm a 38 year old female and I've been on Brintellix since March 2016. It has worked really well. The only problem is I've been married for 16 years and I've never been a jealous person to the extreme I feel now. Even my husband has said that I need to get off of this medicine. it has helped my memory, but its almost ruining my marriage because of how it makes me feel like im not good enough for anything. I started taking it because I've been through some traumatic events in life and I have trouble remembering a lot, but I'm to the point I'm about to take myself off this stuff because my husband said I've been a manic jealous person ever since I started it. I also suffer from ADD, but no one can really tell because I struggle so hard to be good at everything. I keep wanting to think this medicine is good and I'm the problem but I've never been so jealous. so it cant be only me. it makes me jealous over stuff that would normally never bother me. and I can't take it much longer. please share your experience! I'm almost scared to get off because of how sick these medications can make people. please tell me if you have experienced the same. I know everything affects everyone differently. Has anyone ever taken Adderall XR and what was your experience? I cant take brintellix much longer?
Posted 9/3/2016 6:13 AM (GMT -5)
I take Adderall xr and it works well for me. I am not familiar with the brintellix because I have never taken it. I am sorry it is making you jealous. Have you talked to the doc about this? Maybe you should switch.

Welcome to the forum. This thread is about a year old so I don't know if the people who started it will answer. I hope that you feel better soon.

Jealousy is no fun.

Hugs, Karen...
Posted 9/3/2016 10:36 PM (GMT -5)
Thank u
Posted 2/27/2017 9:34 PM (GMT -5)
25 YR old female, I've tried Effexor, Fluoxetine, and Lexapro. I've been on 10mg Trintellix for two weeks now. First I noticed getting tired. Then I started getting itchy and couldn't stop scratching. It was really bad the first couple of days but then it got better and then returned. I also noticed getting very agitated and being upset with things a lot longer than usual. I am very passive and now find myself getting angry very quickly. I also felt a bit down and I couldn't shake that feeling either. Today is a better day only because I stay in my room for most of the day away from the possibility of being bothered by anything. Still itchy, agitated, and unproductive, and not so upbeat but I would like to stick it out for another two weeks.... eyes
Posted 3/16/2017 11:38 AM (GMT -5)
Hi Seeking Peace,

I've been on Trintelllix for over a year now and haven't notice many problems...but there aren't startling improvements either. I started small (5mg) and worked my way up to 20mg. Unlike other antidepressants, my doc said it hits on all five neurotransmitters as opposed to a few like Effexor and Prozac. This is good news for those of use with manic or severe clinical depression. On the down side, the myriad of side effects are just like all the rest. And according to the article I will link below, it has "little benefit" and "significant risks." By itself, it probably won't do much. You would have to find a regimen that works for your condition, like adding a mood stabilizer or anti-anxiety meds.

Best of luck to you!

https://www.madinamerica.com/2014/12/new-antidepressant-shows-little-benefit-significant-risks/
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