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Sensitive to serotonin?

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Posted 9/9/2013 2:01 AM (GMT -5)
I'm wondering if anyone else has this issue but I think I might be sensitive to serotonin. Except for the antibiotics I'm allergic to, the only medicines I've had negative reactions to can affect serotonin/serotonin receptors in some way. Now I believe that the Flexeril that I've been taking for some time is having a negative impact.

I didn't feel like it was working anymore so my Dr. said that I could take it 3 times a day. At that dosage I started have crazy nightmares that woke me up several times a night, muscle twitches (especially in my left eye that got so bad it started to hurt) and randomly sweating (I never sweat, I'm always cold!). Today I didn't take any of it and sure enough the symptoms had backed off and now I'm going to see if I get some sleep tonight free of the nightmares (if I can get comfortable at all with the muscle cramps).

My pain level has definitely been affected by not taking the muscle relaxer so if I go without the nightmares tonight I'm going to call the office tomorrow to see if he'll let me try something else. I've done some research and it looks like Soma might be worth a try, I think someone on here takes it.

So like I said, I was just curious if anyone else has issues with anything that affects your serotonin levels. This really makes me hesitant to try the Cymbalta.
Posted 9/9/2013 7:19 AM (GMT -5)
I took soma for years with no ill effects. Except I notice the brand name soma was awful strong and made me want to vomit, so I stuck with generic. I got different kinds of generics, and found the ones that said mp58 worked the best. I got a new doc and he doesn't like to prescribe soma, but I might ask for a few. Maybe just one a day. Because they do relax the muscles. If you get it, take it with food. I found if I didn't eat, I felt loopy for about 20 minutes after it kicked in. I guess people figure that is a buzz, I sure didn't like it, but it relaxed my muscles after the loopy feeling left. Different meds work differently on different people, so I don't know if you will get the same effect as I did. Just beware of the brand name, don't take with citrus juice, there is a better chance of feeling ill. I hope you find what works for you.

Best wishes,

Karen...
Posted 9/9/2013 7:31 AM (GMT -5)
I had Seritonin Syndrome after taking Tramadol and Celexa for several years. It just started all of a sudden and really scared me. When I mentioned it to my doctor, she had me stop the Tramadol as it raises your seritonin level just like anti-depressants do. It can also be very dangerous. So now, I am on Lortab and I also take Soma 3 times a day. I couldn't survive without Soma. As getting by stated, make sure not to take it on an empty stomach.
Posted 9/9/2013 3:25 PM (GMT -5)
Flexiril caused sweating issues with me too.

I have issues with many of the muscle relaxers so the closest thing I can take is paxil. It seems to ease some of my pains.
Posted 9/9/2013 3:36 PM (GMT -5)
Serotonin Syndrome has been mentioned and there is a link in Fibro 101 all about it.  Certain combinations of medications can cause this.  Serotonin is found naturally in our bodies so I don't think you are allergic to it.  But certain medications can cause you to make too much serotonin, I believe.

 

Sherrine

Posted 9/9/2013 9:19 PM (GMT -5)
Anything that messes with my serotonin will cause me to have seizures! I'm not epileptic but the two times I tried taking anything, Zoloft and Tramadol, I either ended up having seizures or other neurological oddities (like couldn't touch my finger tip to my nose when my eyes were closed) so I stay away them.
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