Hi Charity!
Welcome to our community! I'm so glad that you found us!
Although you are not "new" to Lyme, I would greatly encourage you to read through our "New to Lyme? Start here!" thread that sits at the top of the forum as it's packed full of a ton of information!!
Something that could be happening is that you are detoxing too fast for what your body can tolerate at this point. I know for me when I was still quite ill, I had to be very, very careful in what I did to detox. My first efforts were always met with a 3 day migraine!
It kind of made it hard for me to want to continue!! But, I knew that I was completely over run with toxins so I just kept at it, but in gentler ways.
So by taking both Cholestyramine and Activated Charcoal, it just may be too much for your body right now. We always suggest that members only start one new thing at a time, and to give themselves 3 or more days before starting a 2nd new thing. This way (a) you will know which product is creating what issue, (b) you will be able to back off of the one that's causing issues right away, and (c) you will be much less likely to overwhelm your already struggling body with anything.