I only got breast pain on the side of one last week- I believe it was a lymph node. Did a breast lymph massage (googled it) and hasn't returned!

That being said, I also take a progesterone cream for my hormones/ periods, which were abnormal before lyme. It has helped some, but whenever I seem to make progress, the cycles get wacky again. It has not had any negative effects that I can isolate, it has helped my cycle but it takes many months to get into a regular pattern. Sometimes i have a two-week cycle, then 2 months of nothing, then 3-week cycles... but it's all been manageable.

I have painful breasts.

My hormones are very whacked out right now so I'm sure that contributes to the problem. about 2 years ago that I was told that I was menopausal (this was before learning I have LD) although my periods only stopped for 2 months, then returned (they've since been pretty irregular). I was put on progesterone in March and two weeks after starting it I had some spotting but not what I would call an actual "period" (my doctor told me this can be normal). I haven't had a real period since March and I almost feel like if I could have one it would help elevate some of the breast pain (it's so painful that I dread having to shower and take off my sports bra!). The upside is that since starting the progesterone I don't have as many hot flashes, but that's about the only upside for me. Also, like you, my breasts seem somewhat swollen and larger than normal.

I don't have much to add as far as what helps with this because I'm still struggling with this issue myself, but just wanted to let you know that you're not alone.

Hopefully someone will come along soon and offer some suggestions!

Thank you so much girls for your replays!!!

So much good information. And as always - nice to know that I am not alone in this mess... I am also turning 50 this year so it could also be a real menopause coming. But I never get hot flashes. And my periods were very totally regular all my life before Lyme. And now - bang - problems!