Elevated liver enzymes

Hi everyone
I'm really struggling to get the gang of these infections and would like some help. I'm seeing my LLMD in about two weeks, but have got some troubling results from my GP on blood tests.

Generally my liver enzymes are on the rise, and have taken a bit of a leap the last two weeks.
S-AST = 167, up from 48 a couple of weeks ago (reference range <45).
S-ALT = 132, up from 97 a couple of weeks ago (reference range <70).

I'm really starting to get concerned about this. Do any of you have similar problems, and what did you do about it?

I'm currently on minocycline 100mg twice a day + a range of vitamins and natural supplements.

Any advice is greatly appreciated. Do you think I need to stop my treatment? I'm really scared that I won't be able to continue and never get better

My general condition has also been worse the last couple of days with high pulse (can get up to 140-150 just with a quick stroll) and generally feeling crap.

I have heard that milk thistle is some kind of liver support, but I have not tried this. Maybe I should consult with my LLMD before adding it in?

Looking forward to your great advice and experiences

You're not taking anything to support your liver? Geez. Yes, you should be.

I started out with Milk Thistle. After several months of abx, my liver enzymes started to climb. When they went over the top range, my LLND stopped my abx.

They dropped back right away..and instead of Milk Thistle, he had me take Pekana - Apo-Hepat.

They've not risen to high levels since and that was 2 years ago.

It could be partly the abx, but also maybe die-off of the bacteria could be contributing.

Thank you all for your support I will definitely call the LLMDs office on monday and ask for advice

Girlie: I do take NAC and a lot of other supplements. I know I do have some liver support in there since I also showed my naturopath the collection of stuff I'm taking. I don't think it's milk thistle though. Hard to interpret all the ingredients as they are written in german I will look into that stuff you mentioned. Thank you.

Can the die off cause higher liver enzymes? I haven't really felt any herx as I'm not sure as to what it is. All I know is that my general condition moves up and down, pretty much like it did before I started treating. OK days and bad days. Anyways, I'm not sure if I'd spot a herx if it happened anyway. Probably just contribute it to the general ups and downs.

Denver: I'm not on doxy but minocycline actually. I started out with azithromyzin, rifampin and minocycline for two months, but change to a more herbal approach as my immune system is severely weakened. The last 6 weeks I'm only on mino and herbs/vitamins. I didn't have elevated enzymes for the first month of all three antibiotics, but two weeks after starting with only mino I did. There are about 5 weeks in between that are "unaccounted" for, so a bit might be from the protocol. Anyway, the last couple of weeks it has gone up substancially, and I've only taken the mino antibiotic. Really bums me out.

Do you think I should halt my treatment until I get a hold of my LLMD?
Will halting treatment for a few days cause any harm to the treatment plan?
Maybe it's some of the herbs that was added in when I switched protocol, and not the mino?

Thanks for the advice Girlie.
As of this dose I stopped the mino at least until monday if I can get a hold of my doctor.

I really hope it's die off that causes this stress on my liver. That would be some good news in the midst of things.

I'm still curious if anyone else have had a rise in liver enzymes during treatment. It's strange how it helps hearing from other people that have gone through similar stuff

http://www.liversupport.com/warning-tick-repellent-and-lyme-disease-both-stress-the-liver/

Post Edited (PDXtransplant) : 8/26/2017 12:29:07 AM (GMT-6)

My llmd monitered my liver enzymes too, and when they when high, I took a one month break from the "irradication plan" before going back on.

Any dead stuff in you effects your liver #'s - doesnt matter what you used to kill the critters.

I would think you LLMD would understand detoxing- but I lot of them dont from reading here over the years. You might goggle d-limonene to - its an awesome liver detox, but not well known. I use the Jarrow brand- its the be$t.

Some people have liver detox gene impairment. 23andme data interpreted by the Sterling App will have two pages of these listed. If your red (two mutations) in these, detoxing is , in fact, harder for you than other people.

Post Edited (astroman) : 8/26/2017 9:24:00 AM (GMT-6)

RedLabel said...
Thanks astroman!
I hope it's acutally a good sign, that the killing is working. I'm very curious of my blood data as blood was drawn to send to my LLMDs lab at the same time as I did the liver tests with my GP. I know there are no tests that can show if you are improving or not, but I really hope my NK cells will improve now.

Is this gene mutation something you test for at a special lab?

There haven't been many posts about gene dna testing lately, a few years ago when this was new it was more popular with the longer chronic people trying to get better. Some people decide to make lyme a turning point and try to get better than ever before. 23andme test is around $150-200 now I think, then up to $50 to get it deciphered. You can google it. It can be helpful, but not necessary. I dont like health surprises and it was worth my money. It did show some interesting things- non of us are perfect. The test tube human of the future will be perfect (scary).

NK cells as in the cd-57 test? sometimes they improve, sometimes not. I think c4a with c3a are more accurate of general infectious body inflammation.

OK, I tried googling it but I'm not allowed to order the "health panel". Apparantly some rules in my country that forbid them from selling it to me. ****ing government won't help or let me help myself! Maybe for the best anyways. I've had enough health anxiety for now. Doesn't need to add more.

Well, I mean both CD57 and NK cells in general. They were also well under the lower limit.

Thats great to hear PDXtransplant. Not that you got hepatitis, but that everything went back to normal after a break. Do you think it was from the antibiotics itself, or from bacteria die-off? How did you get diagnosed with hepatitis? Just based on the values, or were there some other test that were taken to investigate this?

Thank you for the link and explanation
I hope mine returns to normal soon as well.

I'm on a protocol consisting of products with all kinds of herbs blended together. Something called TBB, DTC, OPC and Energy plus from a company called Makewell.

makewell.de/tbb-plus?lang=en
makewell.de/dtc-plus?lang=en
makewell.de/opc-plus?lang=en
makewell.de/energy-plus?lang=en

In addition I'm on a range of vitamins, fish oil etc.