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Posted 3/1/2019 2:35 PM (GMT -5)
What is considered to be an optimal b12 level? The last time I had mine checked, it was 330 out of 200-1100 pg/mL. Quest put in the notes: Although the reference range for vitamin b12 is 200-1100, it has been reported that between and 10% of patients with values between 200 and 400 may experience neuropsychiatric and hematologic abnormalities due to occult b12 deficiency.

I have started b12 injections on my own without a doctor, and after the first one I got an instant headache and got really tired, but it helped stabilize my mental symptoms. I'm considering adding methyl-b12 sublingual because I am heterozygous MTHFR and feel I could absorb that form better. Are the shots worth continuing, and possibly pursuing my insurance company paying for? What would have caused that bad initial reaction?

What level would be good to get to? I really think it could help my bipolar/depression symptoms as well as fatigue if we could get it higher. I know I am more apt to having low b12 because of intestinal parasites and a very restrictive diet.

Thanks for your input.
Posted 3/1/2019 3:02 PM (GMT -5)
When I first tested prior to knowing I had lyme disease, mine was over the top end of range. My LLND at the time said "fill your boots with b12)"

Now it's just under I think...I'd have to check my recent test.
Posted 3/1/2019 3:20 PM (GMT -5)
i would be careful taking large b6 or b12 doses for a long time....


https://cancer.osu.edu/news-and-media/news/long-term-high-dose-vitamin-b6-b12-use-associated-with-increased-lung-cancer-risk-among-men

check your levels before taking huge amounts for years....
Posted 3/1/2019 3:43 PM (GMT -5)
mpost, I mean I just started b12 supplementation. So I don't think that will be a problem. I don't plan to do it for years. Just until we can get some levels higher.
Posted 3/1/2019 7:06 PM (GMT -5)
I also had over the top of the range B12. Not sure if it ws because I took B vitamins though
Posted 3/1/2019 7:45 PM (GMT -5)

mpost said...
i would be careful taking large b6 or b12 doses for a long time....


https://cancer.osu.edu/news-and-media/news/long-term-high-dose-vitamin-b6-b12-use-associated-with-increased-lung-cancer-risk-among-men

check your levels before taking huge amounts for years....

Geez - it’s hard to know what to take anymore.
Posted 3/1/2019 7:57 PM (GMT -5)
My B12 was at 1600, at one point. Now is at 550. Girlie said it right with "it's hard to know what to take anymore."
Posted 3/1/2019 9:58 PM (GMT -5)
If you’re MTHFR , remember to avoid folic acid, take a methylfolate so you can convert the serum B12
Posted 3/1/2019 11:47 PM (GMT -5)
Village Crazy Lady, the cyano b12 injections wouldn’t have folate in them would they? I am wanting to start a methyl folate and methyl b12 supplement. I am asking my ND about it next week.
Posted 3/2/2019 2:37 AM (GMT -5)
One must remember that during the methylation pathway, DNA is produced. If you push that pathway by supplementing, there are certain subsets of people that will have an increased chance of more transcription and translation errors. Those errors may not be corrected in immunodeficient people and cancer can form. The same thing occurs when you eat animal protein, you are going to push that pathway. Many people with Lyme, Babesia, or other chronic infections have a state of immunodeficiency.
Posted 3/2/2019 7:00 PM (GMT -5)
Georgia Hunter, that’s interesting. I’ve never heard it put that way. I just need to see a doctor who can read my genetics and fix my detox pathways then. I have one in mind.
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