Girlie said...
How does it work?
I'm not 100% sure, but I'll tell you what I know. I believe there has been great success, but it's still in its trail period. It is FDA registered, but not FDA approved. Basically, I think I'm a guinea pig. However, if LL-37 proves to be effective, it could be a game changer in the way Lyme is treated. I believe our body produces LL-37, so this is likely to be an enhancer.
Below is a list highlights given to me on a handout. I think the info is my docs notes that she shares with patients.
I take a very small dose of LL-37 (.1ml) with an insulin needle, once a day. Shot goes in a fatty area. I take it in the outside of my thigh. I don't like shots, but this is fast and easy. Same dose for 50 days. At the end of 50 days, the does could stay the same or increase, if I'm correct. It's not a life-long injection. It's to get the immune system to work more efficiently, I think.
LL-37 is an antimicrobial peptide which belongs to the cathelicidin family. It serves as an important role in the first line of defense against infection and systemic invasion of pathogens at sites of inflammation and wounds. LL-37 has been successful in promoting would healing but it may play a negative role in atopic dematitis and psoriasis.
*It serves and an endogenous antibiotic that is able to rapidly kill an unusually broad range of bacteria, fungi, parasites and viruses.
*It directly disrupts prokaryotic cell membranes.
*It has multiple modes of action including immune modulating effects
*boosts mesenchymal stem migratory behavior and immunomodulatory effects (immune balancing)
*significant anit-biofilm activity at low levels so it helps the effectiveness of antimicrobial therapies.
*antimicrobial peptides are synergistic with antibiotics and reduce the development of drug resistance
*Blocks adhesion of candida ablicans to sell surfaces
*Effective against free borrelia spirochetes and cystic forms
*Even low doses block the bioactivity of endotoxins and neurotoxins
*Well-tolerated, very safe with few side effects and a large therapeutic window
*Caution with autoimmune disease at high doses, as with many immune modulators.