Questions Regarding Ivermectin

Are you taking the IVM for parasites or to combat Lyme? Parasites cannot really create resistance very quickly, too large.

The horse paste is literally the exact same drug humans take, made by the same company in the same factory.

I don't know about dosing, you can find that info out there though.

i am interested in Ivermectin also

unfortunately, just because ivermectin is classified as an antiparasitic - does not mean that we can assume bart will be sensitive to it as a single agent.

its probably better to think about that classification more of just what the drug was originally designed to do ( we still do not know from a scientific standpoint how it affects Bart or by what mechanism as far as i am aware - but several antiparasitic and antifungals are proving effective in vitro )

i think the safest course would be to use it alongside other antibiotics or possibly along with other antimicrobial bart herbs like houtt and sida ( though that is not known or tested either) until we know more -

the numbers would suggest that the more organisms there are in the body and the more often they reproduce - the more prone they are to developing resistance to abx ( all other things being equal)

bart is v v small ( 400 can infect a single red blood cell ) and also infects many tissues systemically, and is therefore present in huge numbers.
it reproduces around once per 24hrs i think - so this would give it a high potential for developing chance mutations under environmental pressure.

Garzie: “ unfortunately, just because ivermectin is classified as an antiparasitic - does not mean that we can assume bart will be sensitive to it as a single agent. “

Isn’t it usually prescribed for Babesia? (Not bart)

Girlie said...
Garzie: “ unfortunately, just because ivermectin is classified as an antiparasitic - does not mean that we can assume bart will be sensitive to it as a single agent. “

Isn’t it usually prescribed for Babesia? (Not bart)

good point! - not sure why I assume CWL was targetting Bart - maybe i just confused the post with another.

but in any case - i don't think we really know what works with what well enough yet -

I have been reading a lot of posts recently from people taking antiparasitics like Fenbendazole and methylene blue for Bart ( MB - originally used as an anti-malarial before newer drugs became available) and I think Ivermectin comes into this category also.

back to Babesia - i don't know much about it I'm afraid - as it never been a target organism for me to read into in any depth - mainly due to lack of any high fevers in my case ( but that may not entirely rule it out it seems - and recently the UK found a babesia organism called Babesia Venoratum in sheep!).

but it's a pyroplast organism in the same family as Malaria as far as I know - and since malaria definitely develops resistance to every anti-microbial used widely at some point - I would say its best to assume that babesia may do the same.

in fact, a quick google for babesia and drug resistance found this article that details various combinations for the various babesia species and their effectiveness in animal trials

http://www.antimicrobe.org/b51.asp

quote:
" Atovaquone monotherapy leads to the development of drug resistance but not when combined with azithromycin (43). "

of course, we don't know whether ivermectin interacts the same - but i would say the precautionary principle applies

gfields said...
I believe I did read that Ivermectin can be dangerous to use if you have a pre-existing heart condition.

Is there a black box warning for ivermectin? Does it cause prolongued qt syndrome like azithromycin?

i was interested in this - when i looked at the ingredients of the horse paste versions of ivermectin on amazon i was a little concerned to see there was as much Titanium dioxide in the product as there was ivermectin!

i am pretty sure Titanium dioxide has been found to be toxic - I guess its only in there to make the paste nice a white in color -

is this a concern ?
and
has anyone found a brand without it?