Hypercoagulation - lab test results

We have a phone appt w LLMD tomorrow but I’ve been reading over Blakeley’s lab results tonight. Markers if coagulation have been high before and she has been taking Nattokinase, lumbrokinase, and bromelain supplements for prob a year. This current report shows her prothrombin fragment 1+2 at >4800. (Should be less than 326). That is extremely high and concerns me greatly. The Antithrombin complex is also high at 14.6 (should be less than 4.3)

So, with her already taking the supplements and it still being so high, I have read that an option could be heparin therapy. Of course I’ll wait to see what dr says but trying to know some info ahead of time. I have read through some of the threads here on heparin but they all seem years old.

Anyone currently here has taken heparin? Or know of another treatment used for helping this hypercoagulation? Any info at all about this is appreciated.

i do not know a great deal about those particular tests.

the bodys coagulation pathways are quite complex wit many measurable markers.

however, when i read you post and saw markers 10x over the range it made me think something along the lines of Ant-Phospholipid syndrome ( APS) also known as Huges Syndrome may be involved

in this condition, the body produces antibodies to substances naturally present in red bloood cells and triggers hypercoagulation disorders.

the root cause for this auto-immune condition is not well understood by modern medicine but it does seem to be on the rise.

it could well be that an intracellular pathogen like Lyme or co-infections could be involved. there are also some people that are more disposed to the condition from a genetic perspective.

i looked into it when i had some mildly outside range coagulation tests and misshapen red blood cells on a blood smear after some re-occurring hemolytic anemia and gallstones - but I now think it more likely I have coagulation issues from Bartonella as the root cause as it can also cause red blood cell shape irregularities,

your regular primary care physician can run basic tests for APS - so I would start there

but like so many things some people are confirmed with APS even though negative for the antibodies that are normally tested ( there may be other - as yet undiscovered antibodies - that cause the same thing )

there is a Huges syndrome support group on HealthUnlocked that seems quite active.
will try t find a link - this one i think
https://healthunlocked.com/hughes-syndrome

Ok Thanks to all. Dr said today that she wanted her to change the supplements to a different version/brand called fibrinex. She wants to retest again and see the trend bc she typically doesn’t like to put someone on prescription blood thinner without trying everything else first bc it is not as simple as it sounds. I guess that means dosage or something. Anyway, I was highly concerned about those numbers but dr seemed not to stress too much over it yet.

Bluelyme, are you saying she could take s.boulardii and slippery elm as added supplements? Is there bee venom available without stinging, easily accessible in supplement form?
She has been on lumbrokinase (dr mercola brand I think) for many months.
Advice on the best way to determine the cause?

Again today, it’s so hard not to worry about pulmonary embolism or something like that when she stands up and cannot get a breath, feels faint, and starts a coughing fit. Don’t think she’s done that before. It’s so hard to know is this due to Babesia shortness of breath or something immediately life threatening.

useful summary article on hypercoagulation in general in Lyme or chronic illness here -
see better health guy website - about 1/3 of the way down the page - Dr Ann Corson
https://www.betterhealthguy.com/tfim2020

"Treatment: reduce inflammation (omegas, detox, GI, drainage, infections, hydrate, clean diet, exercise, reduce stress), reduce insulin resistance (diet, exercise, minerals, herbs), decrease platelet activation (omegas, E, ginkgo, herbs like Dan Shen, anti-inflammatories, antioxidants, remove viral infections and toxins), dissolve excess fibrin (Heparin, Lovenox, fibrinolytic and/or proteolytic enzymes starting low) use herbs/nutraceuticals/homeopathic immune modulators, eliminate infections and toxins such as mold/glyphosate/EMRs; address genetic weaknesses (may need enzymes during periods of physical or emotional stress for life)."