My most serious question here in my high # posting history. Have several double Alzheimers genes....

My first time going public with this anywhere. Till now, no one new but be and the gene Dr who didnt have the guts to tell me when looking at my aprox (400) 23andme test results six years ago, skipping this part(!) on purpose.

Well I figured it out on my own soon after. Its been brewing in my thoughts since then.

Here I am presenting this bad news to strangers.

My dreams of a comfortable and "sane" retirement have a high probability......of going down the drain. We never know what will happen,but I might, and certainly hope im lucky enough that it doesn't go badly..........

My older sibling are not very mentally strong people, have their own health issues since they are older, and will probably try to avoid this conversation if and when I bring it up. One older sister has brain thinking problems. They are not good self health advocates either. They dont even know what gene testing is.

I will be 60 in a few years. I have other problems that can make brain fog to : the left overs of these infections and hashimoto thyroid that is hard to control, and Primary immune deficiency: Hyogammaglobulimia , only one in a few towns around probably. (1 in 30,000 have this by most modern counting, was 1 in 50K before better testing 20 yrs ago).

I have always tried to maintain good physical health, was a pro level individual athlete (didnt get rich) even with lyme and hashimoto in 20's and 30's and still oddly look 15 years younger, but....my insides are not so great of condition at the cell level. As far as my brain working in the past, It did in between "lyme episodes" and I have two US patents; I can technically list "inventor" on a work resume lol., all that said, Im a regular guy.

Im not sure what to do. I have no one close to help if and when I might need it in the future if things go bad fast vs the natural gradual way of life decay.

When I finally go to a brain Dr, it/I will be labeled on my medical chart forever. It might be time though. They now understand what the unfortunate outcomes are with "double red copy" (positive) Alzheimer genes (four of them too).

My parents did not have evidence of this but died of other causes years ago (cancers).

This feels like a waiting game like no other.

***In your spare time, please mentally put yourself in this situation and think about what you would do. ***

Ive reviewed my post a few times; guess ill just get over it and post it.............

It was hard to write this, its my reality and it sucks.............guess Im screw#d

Thank you

Astroman

I’ve been through the dirty genes course from Dr. Ben Lynch / seeking health and did the strate gene report.

While it’s helpful data to have - genes are correlative not causative.

Prevention is your best friend here. Great data around IR saunas too.

Rainy, yes that one (double copies ) and 2-3 other lesser known Alzheimer genes.

I have experience with brain fog from Lupus. In my case, significant measured cognitive decline that granted me disability income. I have since recovered most, but not all, of my previously high-functioning brain. But concerns of a relapse in this area keep me looking for preventatives!!

I recently came across this diet that you might find of interest.
https://www.healthline.com/nutrition/mind-diet

Best wishes,

Also wanted to share what my previous doctor told me.

She said that after a head injury (she felt that Lyme brain was a head injury) - the brain can continue to heal for 10 + years after the brain injury happened

I do know that mine is better now than 3 years ago….
But so far not as good as it used to be. My fingers crossed that it my brain will improve some more….

saraeli said...
I want to chime in that physical activity is supposed to be highly protective for the brain, so your lifelong level of physical activity is really fantastic. Do you do anything else that is supposed to forestall the onset of dementia, like crossword puzzles?

That is something I do when I don’t want to watch tv.


My husband and I started doing crossword puzzles when we got bored on the ferry. This was when we went to the mainland several times in the last year for a hockey game and a few concerts.

saraeli said...
I want to chime in that physical activity is supposed to be highly protective for the brain, so your lifelong level of physical activity is really fantastic. Do you do anything else that is supposed to forestall the onset of dementia, like crossword puzzles?

I don’t do crossword puzzles, but in addition to my regular job I also do side mechanical work in my home shop which requires a lot of thought and planning to take things apart and put them back together, In addition to fixing the problem.

But I’m sure I won’t be doing the above forever so I should probably find something a little more indoor snd age friendly like crossword puzzles. Video games would probably be more my style, but that’s more reaction skill versus spatial skill.

Funny thing is my lyme and Hashimoto brain does feel a lot more clear at night or anytime after I’ve done physical work or exercise. In this case tonight, the customer was also a past acquaintance, and I was amazingly naming off past names we both knew decades ago very easily. This morning, I would not have been able to do that.

Thinking clearly before noon is not a skill I have. When I do have word and memory recall problems it’s usually before noon.

Post Edited (astroman) : 6/21/2024 9:36:49 PM (GMT-8)

Astroman- I tried to ponder what I’d do in your shoes… I’d definitely pay attention to Alan Macdonalds findings on Alzheimer’s and nematodes. That’s treatable. Have you tried methylene blue? It could be a very beneficial addition. Not only does it shut down bartonella but has been shown to heal neuronal and mitochondrial damage. Stacking this with other mitochondria support supplements (which have also been shown to heal neuronal damage) should only enhance the anti inflammatory effects (PQQ fisetin coQ10) Other ways of mitigating risk, Lions mane and other ways to increase BDNF (yay exercise is a big one, a variety of peptides therapies like Selank) and BPC-157 can help. Fish oils and healthy fats. Let’s keep looking for things we can do to nourish our brains and prevent inflammation.

Me again

I can't believe I forgot to mention Theracurmin. It's a highly-bioavailable curcumin product "that lowers TNF-α, showed enhanced cognitive performance and decreased brain levels of amyloid-β plaque and tau tangles"

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7739965/

I believe most of us are aware that curcumin is great for many, many other aspects of health as well.