Yes - Lyme, especially chronic Lyme causes adrenal and thyroid issues for some. I have both and am still trying to recover from them.
I use Armour for my hypothyroid issues and Standard Process's Dessicated Adrenal for my adrenals.
If you believe you are starting to enter into adrenal fatigue, I implore you to make sure to get them supported properly. I ended up with severe adrenal fatigue which brought down my thyroid.
The two sites I have found with the most accurate information and the easiest to read through and understand have been:
Stop The Thyroid Madness:
www.stopthethyroidmadness.com/adrenal-info/And Dr. Lam's:
www.drlam.com/articles/adrenal_fatigue.asp Many find that they can take adaptogenic herbs to help with minor adrenal issues.