Posted 12/9/2015 1:29 PM (GMT -5)
I don't have any experience treating Babesia - but Dr. M.R. from Seattle also suggests adding Bactrim if the Mepron plus Zith isn't working.
"Atovaquone Combinations
Atovaqone (Mepron) 750mg/5ml combined with one of the following 5ml two times a day. In 1 to 2 months if night sweats or other babesia symptoms are not improving then increase the dose to 10ml two times a day. Combine it with one of the following:
azithromycin (Zithromax) 500mg 1 time a day,
clarithromycin (Biaxin) 500mg 1 pill 2 times a day,
doxycycline 100mg 2 pills 2 times a day, or
minocycline 100mg 1 pill 2 times a day.
In addition if these combinations are not working I sometimes add
sulfamethoxazole/trimethoprim 800mg/160mg (Bactrim DS or Septra DS) 1 pill 2 times a day to create a 4 drug regimen. (Atovaquone/proquanil (Malarone is two drugs in one pill)."