I was just doing some gene research and read this and thought of you. Not sure if you have done 23andme to check if you have this SNP. The article was by Suzy Cohen. I included the passage that may be of interest and the full link below. I have this SNP btw. I have not taken a fluoroquinolone as of yet. If you do have this SNP it may give you further reassurance in stopping the drug.
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Avoid fluoroquinolone drugs if you have a SNP in CYP1A2 (like me) because these drugs are strong inhibitors of the gene and the drug will build up quickly. Strong inhibitors of the gene reduce clearance of the offending medication which gets metabolized through that pathway. In my example the “FQ drugs” or fluoroquinolones as they are known pharmaceutically are drugs that get metabolized through this pathway CYP1A2, and if you are homozygous positive (+/+) it doesn’t work well to begin with so the FQ drugs build up, and they get toxic quickly. They have a black box warning already from the FDA for tendon ruptures. I wonder how many of those people with severe side effects from FQ drugs had a SNP for that?!
suzycohen.com/articles/snpsmethylation/