Is this a herx? Bladder issues and insomnia

Sorry in advance if this is stupid... I have noticed that I can tolerate antibiotics by themselves just fine. I can even handle the addition of plaquenil to antibiotics. But every time I try to add in a second antibiotic (like bactrim, ceftin or antifungal like Tinidazole), my insomnia comes back as well as my urinary issues. Basically going pee like every 15-30 minutes with discomfort after. I did not ever correlate this to a herx but thought the high load of abx were irritating my bladder. But then it wouldn't cause insomnia? Does it make more sense that the toxins from die-off are irritating my bladder or nervous system?

I detox a lot but obvoiusly need way more to deal with this. So while I thought I was not herxing, maybe this is MY body's version of a herx.

It's amazing how long it takes to work all this out.

What are you doing to replenish gut health?

Maybe first check that you aren't developing symptoms of interstitial cystitis (I get flares that wax and wane with treatment). Seems to be very common in Lyme and/or pathogen patients - which I never knew way back when!

I mention it because with IC, you have to yank acidity! Most people run for the cranberry, etc...but it will irritate and hurt the bladder lining more. When I have a flare I can't take any lemon water....or acidic anything (citrus, vit c, etc).

DMannose is supposed to help IC patients.

Not saying you have it...just maybe look into it because it isn't all that uncommon and, unfortunately, many women go for the old UTI protocol, which is the exact opposite you want went calming down an irritated IC bladder.

Is insomnia induced by having to get up all night and that awful bladder feeling or does it stand alone?

I thought I originally had IC a year ago, it went away after 6 weeks then came back when I developed lyme symptoms. Then went away again. It has been fine mostly for the past 6 months just flares up when I take more than one abx. And its never as bad as the first time. Plus the insomnia with it makes me think it may be toxin overload.

I just read this thread through for the first time.

The fact that your issues correlate with your meds intake makes me think they are herxes.

I herxed with all sorts of bladder issues and things were much worse if my thyroid was low at the time. I can't say I found anything that worked to eliminate the bladder issues except treatment and time.

Increased detoxing is always a good idea.

Some LLMD's pulse tinidazole....