LymePickle said...
Georgia - Binds to the same receptor, which receptor are you talking about? You raise a good point though... I shouldn't point the response in my body to just quercitin, but potentially it could be egcg, the L-arginine, or the quercitin... In addition to that I was also slamming it with high doses of monolaurin, and ACS 200 spray. I just read a few articles saying quercitin could bind to the same spot in bacteria as fluoroquinolones, so I was just curious about the possibility. I was thinking if you have read anything about this Georgia? I know you like to read lots of research papers. After this week of intense treatment my foot pain and aches, inflammation, it was ALL gone! But then I stuck with JUST the herbs (Houttuynia, sida acuta, alchornea, etc...), and symptoms slowly came back. So no ACS200 as I ran out, no monolaurin as I just got lazy taking that, and no l-arg, quercitin, or egcg.
I've read several papers on the subject. They both bind DNA Gyrase which is the protein inside the bacterial cell that allows the DNA to supercoil. DNA is actually pretty big compared to the organelles that are inside the cell and to get it all to fit, it has to be coiled just right. By binding DNA Gyrase, it can't coil and the bacterial cell dies.
There are things we must remember about
the research articles we read. Some people have normal immune responses, some people have suppressed immune responses, and some people have heightened immune responses. Many of us have lowered immune responses and we may not react the same as the "normal" people in a study. We have a much smaller therapeutic window that we must fit into. Methylcobalamin is a good example. It helps many people and increases their methylation pathway, but for some hypermethylators, it is too much. The window for success for many of us is just a lot smaller and a little too much of something and we tip to the bad side effect side of things. We'll try something and say "Oh, that caused me all kinds of problems" when in actuality, we need it but just in a lower dose. Quercetin fits into that category.