/news.northeastern.edu/2015/06/researchers-discovery-may-explain-difficulty-in-treating-lyme-disease/
Same research group,later paper. news.northeastern.edu/2016/03/researchers-investigate-four-promising-new-treatments-for-lyme-disease/

I did about 16 weeks of Mon, Fri, Weds IV Rocephin and found it to be very effective. I typically was in the IV lounge with the same people most of the time and everyone was feeling much better as the weeks progressed.

Do you have Dr. H's newest book? I think he references studies in there. My book is on loan to someone right now, so I can't look it up with you.

Much more so, thanks. In vivo would be nice but that may be a tall order so I am open to more opinions and experiences.

I am also trying to determine a justification for pulse dosing Tinadazole. Does it really work as well as they say or are the doctors simply scared of using it on a daily basis?

Have there been any reports of negative consequences from daily tinidazole use? I know about the black box warning for cancer but I don't believe it shouldn't really have one. I am certain this was done as a legal precaution.

I seems at the end of the most recent pulse dose of Tinidazole I backslid a bit. Nothing major but I could feel it. I am concerned with pulse dosing leading to resistance. So if anyone has more info on Tinidazole or even an anecdote from their own use please chime in.

As an aside on an up note, I had my third day in the last 3 decades with little to no inflammation nor need for any pain medication (Kratom). I think the Augmentin treatment is finally working for the back pain cause by P. Acnes in my case.

The addition of a pinch of Epsom salts in my drinking water along with 6000mg of Flax oil split into a morning and evening dose has made a rapid (one week) and huge improvement in reducing my inflammation when compared to Stephania herb or turmeric which I regret to say just doesnt cut it for my inflammation.

And my Rifampin, Mino, Azithro, Biaxin, and more Fluconazole, all arrived from India yesterday. Strange as it sounds it felt a bit like Christmas without the snow!

Girlie said...

And you do know that Dr Jemsek only pulses - has been for many years - and he gets results. Other LLMD's follow similar protocols to his.

Don't tell me he pulses Doxy? That was a big error I made early on, but it was involuntary. Early on when I was extremely ill, Doxy and other drugs would give me kidney fatigue and I had to stop them for a while.

Now I think it wasn't the weakness of the kidneys but an infection in the kidneys.

Girlie said...
ChickenArise - I'm not clear about what happened to you when you pulsed doxy?


Dr. J. pulses all of the antibiotics he uses....i don't know if doxy is one of his choices...most likely is.

I build a resistance or tolerance, I am not sure which. I am on it again but it takes 200mg bid to have any effect now. So I plan to try to make the 90 day mark or cross over to Mino (so I can begin Rifampin) for the balance of the 90 days.

Do you mind if I ask how you tolerate the tinidazole? This will be the next abx I add to the mix (already on Ceftin and Doxy). It will be 500mg / twice a day (1000mg total daily) pulsed, 3 days on, 4 days off. I will start with just one pill (250mg) a day, but it still scares me a little. I heard it can be a doozy.

mm57553 said...
Do you have Dr. H's newest book? I think he references studies in there. My book is on loan to someone right now, so I can't look it up with you. Do you mind if I ask how you tolerate the tinidazole?

No I went with William Rawls new book and Buhner Bart and Mycoplasma, his new book was my runner up choice and I only allowed myself two, but I respect the guy. I've heard him speak and he seems to know Lyme.

Odd that the two books I chose are both more geared toward natural approaches and here I am using mostly allopathic. But should the drugs fail me, at least I will have have a backup plan.

The first day Tini was a herx at 500mg once daily, afterwhich it was uneventful and I questioned if it was doing anything.

I tolerated it well and each time I revisited it, I took the dosage up (except when it coincided with Nitazoxanide) and the last was 500mg tid.

All of my use has been 2 weeks on and two weeks off.

In the unfortunate event I get cancer I would suspect the mycotoxins from the mold before Tini.

GIRLIE: The odd thing is Doxy does hit Bart to an extent but Bart comes back. I am fairly certain I am dealing with ocular bartonellosis right now. I was forced back on the Doxy from the epidydimal flare up and although it is working for both issues I know I am going to need the Rifampin to resolve this.

Girlie said...
I don't know who you're asking...but I'll answer...

I was prescribed the tinidazole only two days a week 500 twice daily on those days...and I never noticed anything while on it.

I was on Ceftin when I pulsed the tinidazole.

Thank you! That makes me feel better.

Rikky1 said...
Flagyl or Tinidazole hits bacteria and parasites so if you're dealing with Lyme or co-infections it will kill it. Whenever I take my 2 consecutive days of Flagyl every 3 weeks (500mg 2x/day) it kicks my proverbial butt.

When I added doxy to my rifampin to treat bartonella it hit my chest nerves pretty hard so hard it made me tear at times. After a few months the chest pain is still there but more tolerable so it did help knock back what I believe to be bart.

Hmmm...interesting that I don't recall any herxing from the tinidazole. It was a while ago...though...