Those who have MTHFR mutations

For those that have mthfr mutations..did treating the mutation with supplements bring out any symptoms? Been taking methylfolate and it's bringing out some symptoms, I like to think that it's purging some toxins through my body since I have been backed up so long from being compound heterozygous.

I added in both methylfolate and methyl B-12 (they kind of go hand-in-hand) and there's no doubt it's helped my body detox easier -and yes, at first it made me herx! That's because I was suddenly able to detox so much easier that more toxins were being moved through the liver and other detoxing organs.

Do be sure to stay on a 'smallish' dose though, unless you can evaluate and see that you need a higher dose. It doesn't take much for me.

Also, you may need to up the other forms of detoxing you are doing for a while until the toxin loads come down more.

Hi LB!

It imperative that I keep costs down as much as possible, so my brand choices may not be the best, but they are working for me.

I use Doctor's Best brand "fully active B-12" - 1,500 mcg (1 daily)
And, Solgar brand (methyl) Folate 1,000 mcg (1 daily)

I hope that it's helpful! I was blessed by someone on this forum to guide me on this too!