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Vitamin D Causing Fatigue

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Posted 8/14/2017 1:55 PM (GMT -5)
I'm able to take 2,000 IUs of vitamin D each day. Higher doses cause fatigue and migraine, worsening as the dose increases. When I try to search for info on what could cause this I get flooded with results about vitamin D preventing fatigue.

What could be causing this? Doctors haven't been able to explain it.
Posted 8/14/2017 2:41 PM (GMT -5)
Really they can't explain.. lol. D3 is a known immune booster/immune modulator - acts by forcing macrophages to release antimicrobial peptides like cathelicidin. Probably your level of D25 is low(around 20..30), so to keep getting the herx from D25 its level should stay low. Also watch out for hypercalcemia with D25 dosing.
Posted 8/15/2017 12:37 AM (GMT -5)
acarined have u tested your 25-OH vitamin D ? How do you know how much vitamin D to take ?


After one year of taking 2000 IUs daily i tested my levels AND I WAS DEFICIENT. I had to boost to 4000 IU daily and also took vitamin K and it jumped from 30 to a more safe 50 after 3 months.

i do not eat dairy at all, but i eat nuts and my calcium levels are close to upper range, u need to be careful with that part when taking vitamin D for many months... hypercalcemia can give u damage to your arteries and kidneys
Posted 8/15/2017 1:02 AM (GMT -5)
Would it be better to sit in the sun for 15 minutes a day?
Posted 8/15/2017 1:59 AM (GMT -5)

10LymeB said...
Would it be better to sit in the sun for 15 minutes a day?

That's what I would think, too. Nature always trumps supplements. Besides, is low Vitamin D a CAUSE of illness or a RESULT of illness? (Rhetorical question.)

The Truth about Vitamin D
Pam Popper, PhD, ND on Vitamin D Supplements

Post Edited (The Dude Abides) : 8/15/2017 1:02:10 AM (GMT-6)

Posted 8/15/2017 3:00 AM (GMT -5)
> Would it be better to sit in the sun for 15 minutes a day?

Its mostly worse - sun most of the times(but not always) will give you immune suppression, while D3 gives immune stimulation(via rapid D 1.25 conversion) effect(unless your D25 is high). Just google D3 lyme herx, read the data and you'll get the whole picture.

Just watch out for hypercalcemia with D3 pills. I'd pulse D3 every 3..4 days to be safe on this.
Posted 8/15/2017 9:29 PM (GMT -5)
I've stopped taking D3. It wasnt doing anything beneficial that I could determine. Many here have been supplementing for up to a year with no improvement on their Vitamin D levels.

I was concerned it could be doing more harm than good.
Posted 8/15/2017 10:31 PM (GMT -5)
Well, learned something (again lol). High blood calcium levels possibly from D3. And high blood calcium is BAD for bones?, what? how does that happen? - you'd think it would be the opposite.

My parathyroids were fine, so it might be my D3 supps. Getting D3 up to 60 had no benefits that I could tell.
Posted 8/16/2017 3:26 AM (GMT -5)
> And high blood calcium is BAD for bones?, what? how does that happen?

Looks like for minority the body chelates calcium from bones(hello osteoporosis) to destroy the extra D1.25 which is generated due to the rapid D25 -> D1.25 conversion as a result of D3 supplementation.

Thats why many supplements for D25 come with calcium. Which is not without the risks too - google D25 calcium supplement risk of kidney stones. A lot of research..

So yeah, its complex. sad

p.s. there still could be the benefit of cautiously pulsing D3(if D25 is very low), checking D25 blood levels to prevent overdose and PHP plus PTH hormones to avoid hypercalcemia(osteoporosis).

Post Edited (Dmitry) : 8/16/2017 2:31:41 AM (GMT-6)

Posted 8/17/2017 12:55 AM (GMT -5)
Great points Dmitry and astroman.

I have also learned that if calcium goes up the body's Magnesium goes down.

I have been receiving so much benefit in less than one week
from increasing my Magnesium to bowel tolerance. This is accompanied with Flax seed oil which augments it.

Inflammation of the back muscles has decreased substantially. Inflammation from eating too.

I plan to start a thread as well as shout it from the rooftops of all of my other outlets soon. I just want to evaluate it for a few more days.

Kratom use decreasing rapidly. Fingers crossed.
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