my llmd feels that alot of sweating can be bart....in fact he feels most of lingering symptoms are bart

I have occasional night sweats. They started in college so has to be bart or myco. Over the years would go through spurts of having them. Now, when I start certain abx I get them for about a week (mino, doxy, azith).

I had no sweats with rifampin, bactrim, ceftin, omnicef or malarone.

NicHostetler said...
Yeah I’ve been taking Zithromax for awhile now because I wasn’t combining it with the mepron for babesia. Now I’m also having burning and numbness in my stomach on the left side.. so weird..

Hey Nic, sorry to hear you are feeling so terrible. When did you stop your last round of Mepron/Babs treatment? It took me almost 3 weeks after stopping Mepron to feel better. Were you unable to switch to another Bab med to get the recommended 4 months of treatment in? I started taking NAC as a supplement and that has really helped.

NicHostetler said...
I stopped it Thursday morning. So you think I could still be feeling side effects from the mepron? I thought the Rifampin lowers the effectiveness of that so I figured it kind of cleared by now.

I am going to take artemisinin and CSA to help keep treating babesia while treating bartonella.



Does anyone know what this burning sensation could be? Its terrible.. Its on my stomach.. kind of feels like a sunburn with numbness.

Mepron half life - 2-3 days , so stays in your system for a long time especially if you took it daily, how long were you on it?

NicHostetler said...
I was on it from November to the middle of February and then from the middle of February to the middle of march.

Hopefully then after the mepron is out of my system I start feeling better.

I haven't done the math, but I would think it could be in your system for several weeks...but the good news?
It's gradually lessening everyday...


Hang in there...

Solaris719 said...

NicHostetler said...
I stopped it Thursday morning. So you think I could still be feeling side effects from the mepron? I thought the Rifampin lowers the effectiveness of that so I figured it kind of cleared by now.

I am going to take artemisinin and CSA to help keep treating babesia while treating bartonella.



Does anyone know what this burning sensation could be? Its terrible.. Its on my stomach.. kind of feels like a sunburn with numbness.

Definitely could be the Mepron. With a half life of 2-3 days, 4 half lives could mean anywhere from 8-12 days before it’s out of your system, and then you may need even longer after that for the toxins it creates to clear. I have no experience with the stomach symptoms you mention, do you have acid issues? Does Alka seltzer or tums help?

I think it would be more than 8-12 days...since the amount is building while on it?

I'd have to do it on paper...

It takes about 4-5 half lives before the drug is considered clinically eliminated from your system. I am not sure if the cumulative effect of building the drug up in your system factors into it, BUT, at a bare minimum you are looking at the very last dose of Mepron being in your system for a while. RxList has Mepron half life at 62 hours plus or minus 30 hours (meaning for some folks the half life is closer to 90 hours, or as little as 32 hours). Take 62 hours, multiply that by 5 (for 5 half lives to eliminate) and you get 310 hours, then divided by 24 hours, you get 12.9 days on average. That’s just the Mepron, the eliminate the toxins created and detox can be days or weeks beyond that. It took me at least 3 weeks to recover from the 1 month on Mepron, and I tell everyone that those were the worst 3 weeks of my life. I won’t be touching Mepron again unless my life depends on it (finishing week 3 of Coartem now, much more tolerable at this point, will prob go to malarone after that).

As far as the Bart treatment, I suppose it’s up to you if you can handle recovering from babs rx and starting Bart rx. Listen to your body, consult with your LLMD if necessary, and go from there. Detox as best as you can.

So do both of you think I should probably stop Rifampin for a few days at least and focus on detoxing my liver and then start it back up when some of the mepron has cleared?

Just not really sure what to do at this point...