Still have elevated enzyme: help with genomic, please :(

Hello all,

To put you in context (sorry for those who know my background),
I've been sick for almost a year now, and despite doing several things for detox, I still get abnormal labwork with elevated enzymes.

Prior to Lyme, my enzymes were ok. I've also always been healthy.
- First labwork AFTER Lyme was done 1 month after infection while on 200mg doxy BID. My ALT was in the 70~ (normal range 5-40)
- When I started treating with a real LLMD who did a combination of ABX, my ALT were fluctuating between 50 and 80.
- Things went out of control when I switched to a new protocole with Alinia: ALT went to 200. I had to stop all ABX
- That ABX break lasted 3 months during which my enzymes SLOWLY decreased down to 80 (they never got lower than that).
- Now that I'm back at 80, my LLMD had me restart a light protocole (mino + clarithromycin), and now my enzymes are being at 100 again.
I'm supposed to do lab work every 2 weeks at this point, and if it raise higher than that, I'll have to stop again.

I'm still pretty bummed about all this.
My detox routine has been:
- Charcoal + Clay 2 hours before bed
- Probiotic at lunch and before bed
- Pekana BIG 3
- Lots of water
- Decaf Coffee (recently added)
- I had my first coffee ennema a few days before my last lab
I'm on a Ketogenic Diet; I do not cheat with food nor alcool.
Last thing: at one point during my 3 months off ABX, my enzymes raised gain: when I added Gluthatione capsules to my detox regimen. So I discontinued Gluthatione and things started dropping again.

I did a sonography last week and there no anormality: No fatty liver or anything

I know that I have Lyme and also bart because of symptoms (major feet/toes pain).
I know bart jump in the liver and may cause MILD liver enzymes (see horrowitz article online)

All this intro because I'm still feeling clueless, my LLMD suggest that I may have genetics issues making my detox not good. That there are genomicists that can evaluate and treat me for it.
I feel totally clueless about this... (quite frankly I'm exausted of battling with enzymes on top of Lyme).
Apparently it's about taking saliva and running analysis on it?

Do you think that this is a good approach? I'm so broke because of this, but I'm willing to pitch in more if it's worth it.

The list of specialist my LLMD gave me:
Toronto: Dr. Robyn Murphy Lifestyle & Personalized Genomics Consultant
US: Bob Miller, ND
- US: Shawn Bean

I never heard of any of them...

Post Edited (Alxander) : 2/7/2019 3:07:04 PM (GMT-7)

Hi Girlie, thanks for the reply.

Yes, Apo-Hepat is one of the 3 bottle from the PEKANA BIG 3.

I'm no scientist but I have a feeling that Bartonella has been the issue with my enzymes.
I've asked the doctor if I could add Rifampin to see if it improved the Enzymes over time but she said it was not a good idea, that the Rifampin would make my enzymes go to high.

Considering that I've been on a 3 months break of ABX and that my Enzymes never dropped under 80, I feel like i'm in a catch 22 thing.

If I add Rifampin and go after bart, my enzyme will raise even higher and i'll have to stop treatment.
If I don't add Bartonella focused meds to what I'm having, Bartonella still ravage my liver and i'm stuck with high enzymes.

Note that I've also tried the following to bring the numbers down but discontinued after seeing no results):
- ALA
- NAC

I could ask her even tho she replied to me that my enzyme would go to high, when I first asked.. :-(
One thing she seem to be worried about is that if you stop Rifampin, there's a chance that the bacteria become resistant to it, hence she don't want people to quit soon after starting it.

Ugh... so complicated haha

I'd like to know too, I just went to my doctor today because my enzymes have been inexplicably elevated for a year now! And I only figured that out because my psychiatrist told me! Anyway, I don't know what is wrong because I'm not even treating right now so if you find out let me know. I'm doing coffee enemas and getting a test tomorrow, hopefully they will have gone down, though it's frustrating I have to do them to keep my enzymes down.

jb1994 said...
I'd like to know too, I just went to my doctor today because my enzymes have been inexplicably elevated for a year now! And I only figured that out because my psychiatrist told me! Anyway, I don't know what is wrong because I'm not even treating right now so if you find out let me know. I'm doing coffee enemas and getting a test tomorrow, hopefully they will have gone down, though it's frustrating I have to do them to keep my enzymes down.

Why aren’t you getting all your lab results?

Girlie - I get them but I had no idea this was going on for a year now.

I had looked at them, but only the ones from the past few months that they've been taking. I didn't know they had been elevated since last year.