Nystatin: A must on ABX or not?

I don't know, but my doc has had me on it throughout my abx treatments. Probably a way to hedge. Gut issues often crop up with abx (obviously!), I think it's a good idea to do whatever we can to minimize potential side effects if we pursue these treatments.

If you are taking a high quality probiotic and follow a strict anti-candida diet consider stopping it for awhile. Maybe just rotate it back in every few months to be safe.

Candida and a lot of yeasts that colonize humans have been developing resistance to Nystatin over the years, so it seems wise to rotate with with other treatments or opt for other gut health protocols entirely. There's a lot more to consider for your microbiome balance than what Nystatin addresses anyway. I agree that diet, probiotics, sugar, and some herbal tinctures might be more beneficial for your body overall, and might relieve you of a bit of your pill burden.