Primaquine/Coartem/Stevia a Possible Cure for Lyme Babesia

Charlie55 said...


I'm the evidence along with Dr. H's patients using Stevia with Dapsone and other persister cell drugs.

Don't believe me, don't take the protocol and move on, simple as that. We can debate about this forever, the top LLMDs Dr. H and Dr. J recommend it to their patients. Dr. Sapi has done studies and said it was the most effective herb against biofilms, next to the essential oils by Dr. Zhang
.

Dr. J doesn't include Stevia in his protocols. He prefers Xylitol and Lactoferrin for biofilms.

Sheekster said...
I took primaquine and suprax with Dr. H in California associated with Igenex. Didn't really do anything for me. However, like Charlie (ouch Charlie bit meee, lol) I did some research on primaquine and found that other forum members noted that it was effective for babesia duncani (which is what I have) when used in combination with other anti malarial drugs, and I was using it as a single agent per my llmd, which I did think was strange... I have since switched to Dr J who I believe uses coartem but not primaquine.

Primaquine on it's own may not be enough, again, I took high doses of Stevia with Premaquine and Chloroquine, then Coartem and Daraprim. Then a few weeks break, then hit it again...

I only made it two 12 days the first cycle, then 7 days the next cycle. The herxing and fatigue was so bad I couldn't make it to the 14 day mark with primaquine.

For me, this protocol put enough dent in my infection where I followed up with disulfiram for a few days, then pyrazinamide for a week, then now I'm just smoking a stevia dominant strain of hybrid cannabis.

The cannabis herxing was more violent, however when being on primaquine, I felt like I was ran over by a freight train, I had slept for 2 days straight.

And at times being on stevia dominant strain of hybrid cannabis, feels like I've been up for 2-3 days with very little sleep. I'm still mildly herxing, small violent twitches in every parts of my body.

Once I took Babesia out of the picture, a lot of the biofilms, maybe even more coinfections, maybe even nematodes? I suspect the borrelia infeciton has become a lot easier to treat.

If you really want to get silly, Stevia/Primaquine/Quinine.

Even sillier, I once tried Coartem and Larinate (Artesunate/Sulfadoxine/Pyrimethamine)

My honest opinion is coartem, daraprim, larinate, Artesunate are all pretty save antimalarials. Be careful with primaquine, may have to take folic acid with it like dapsone. And remember about the genetic disorder, some people could get liver damage, but I suspect that's for a very small population and people of special ethnic background.

Primaquine alone wont be enough.

Sheekster said...
did some research on primaquine and found that other forum members noted that it was effective for babesia duncani (which is what I have) when used in combination with other anti malarial drugs, and I was using it as a single agent per my llmd, which I did think was strange...

May be... But again, you didn't combine primaquine with any of the other 3 drugs and herbs I mentioned did you?

Coartem or Artenulate... Both of these pharmaceutical brands of artemsia are found to erradicate borrelia persister cells really well in the john hopkins study.

I also found having a super high fat diet and using Stevia made these drugs probably 3x more effective. Don't give up, there's plenty of other lyme patients that failed with primaquine too, but it seems they didn't use a highly effective biofilm buster... Or paired it up with Coartem... Or used a high fat diet.

Even Dapsone wasn't as effective when just used alone, Stevia or Xylitol made Dapsone a lot more effective.

Again, some of these antiparastics like primaquine may not hit borrelia hard, however it may hit the biofilms hard.

Sheekster said...
I have since switched to Dr J who I believe uses coartem but not primaquine.

Tell him to go over this post, ask Dr. J what he thinks about primaquine working effectively on biofilms because of penetration (strong half life due to better absorption) and the theory it hits the dormant babesia form in the liver.

Rotating Primaquine/Coartem with other persister cell drugs like Disulfiram or Dapsone or Pyrazinamide may be key!!!

These antiparasitics may bring down the biofilm shield, then hit the dormant persister borrelia persister cells hard with a persister cell antibiotic, even Disulfiram will help wake up the dormant forms and pull out the deeply entrenched bacteria even more.

Girlie said...


Dr. J doesn't include Stevia in his protocols. He prefers Xylitol and Lactoferrin for biofilms.

Thank you for clarifying it girlie, amount of typing, I sometimes forget to clarify what particular biofilm busters Dr. J and Dr. J uses. I still haven't even tried Lactoferrin.

Girlie said...

Does Dr. J use Coartem?

I know with Mepron for Babs, he uses Artemisinin. I know Coartem is similar - but a pharma 'version' with a second med.
(Im not saying he doesn't ....but haven't seen it in anyone's protocols ... yet.)

Problem is, I heard the pharmacies in the US don't even carry coartem in the higher dosages, the standard pills are 20 mg/120 mg.

I got my hands on the 80mg/480mg, talk about powerful! No matter how much artemisia you take in herbal form, the herbal pills just won't absorb and penetrate as effectively.

Use two dosages of 80mg/480mg Coartem x2 a day, paired up with darparim, talk about herxing.

I tried two brands of artemisia herbal formulas over the year, absolutely did nothing for me, no herxing. When I had mixed it with other herbals, a tiny bit, but nothing on the lines of Coartem or Artenulate.

Again, I suspect even if you don't have babesia, Coartem or Artenulate with Daraprim should effectively erradicate biofilms and borrelia persister cells, hitting the heart of the infection.

Then you may be able to eventually trickle off with CBD hemp oil/THC cannabis or disulfiram or dapsone.

Be interesting to rotate a high dosage of coartem take a few days off, then do darparim and dapsone.

I suspect you'll have to find the particular combo that will fit what strain of borrelia or coinfecitons you may have, as before I failed with dapsone, pyrazinamide, and disulfiram. Probably was a stepping stone, but didn't hit the multisystemic infection hard enough.

Coartem and Primaquine drugs were on a level for me.

I honestly believe primaquine may kill borrelia persister cells too, but maybe not. Again gotta rotate these two Coartem and Primaquine to make the protocol effective I believe.

Post Edited (Charlie55) : 3/23/2019 8:09:04 AM (GMT-6)

I think considering Dr. MacDonalds' work too, along with my antiparasitics worked so well for the Kinghardt Academy. There may be something more than just the dormant liver form of Babesia in the Liver. Very well may be that primaquine/coartem also destroy nematodes really well. Just like someone mentioned earlier, just a reminder.

jb1994 said...
It's fine if you think Stevia was a big part of what made you better but as I said there is no actual evidence behind it working.

I didn't just use stevia, I used multiple types of essential oils and xylitol. Both Stevia was shown to work on biofilms through Dr. Sapi's study and essential oils was found to work on biofilms in Dr. Ying Zhangs study. A lot of patients from Dr. H are having success, this is what he uses, isn't he considered one of the top lyme literate doctors? Along with Dr. J using lactoferring/xylitol, these were the top doctors in the Under Our Skin documentaries weren't they?

I thought someone posted this before in the thread? And I responded... Remind you this is just my story, I could be 100% wrong on everything. I'm just sharing my opinion.

https://www.healingwell.com/community/default.aspx?f=30&m=4114992

jb1994 said...
Mmm, there's really no evidence Stevia actually does anything to Lyme in the body, only in petri dishes and in amounts much higher than one would typically consume. Nothing for babesia in the literature either. But at least the Dapsone works.

I mean you can go start another post explaining why it doesn't work, maybe others will join in saying it didn't work for them, but does that mean it won't work for others, considering everyone has different strains of borrelia, babesia, bartonella, anaplasmosis, mycoplasma.

Post Edited (Charlie55) : 3/23/2019 3:38:28 PM (GMT-6)

sebreg said...

Coartem has been incredibly effective for me, in fact of everything I've taken it may be the most effective of all of them.

Yes, it's seems to be a very effective against babesia and borrelia persister cells, one of the drugs where I feel extremely energetic while being on it.

I think I remember hearing of a couple of patients that used coartem and the drug not doing much, but I've also heard the majority of patients that made huge progress. From my experience adding daraprim + stevia made an even bigger difference in herxing.

And like someone remarked about nematodes, there may be more going on here than just babesia, I was wrong for saying "other parasites" aren't causing the disease to stay chronic, I completely forgot about Dr. MacDonalds work. This really may another reason why lyme disease is hard to kill. This whole parasitic thing could be more complex then we think.

All I can do is just theorize and what I've experienced by taking the coartem/primaquine protocol. These drugs are the most effective drugs I've ever taken, herxing has been on a different level. And since taking them, targetting borrelia seems to be a lot easier now because I'm herxing a crap load just by smoking cannabis solo, no other drugs.

Two throughts that roll through my mind, I killed off the babesia that was suppressing my immune system or I killed off some nematodes that released borrelia or both.

This disease is just so darn complex, but I think using the proper antiparasitics play an important role with erradicating the disease which could possibly reach remission.

Post Edited (Charlie55) : 3/23/2019 10:30:07 PM (GMT-6)

Girlie said...

I've not taken Artemisia. Artemisinin is quite strong...but not as strong as Artesunate....I had trouble taking the dosage that my LLND prescribed for Artesunate.
(You do mean Artesunate...right?)

Yeah, sorry I misspell sometimes... Yeah I tried Doctors Best Artemisinin in super high dosages, for me the herbal formula did nothing compared to Artesunate. I guess there's three different spellings of the pharma name Artesunate and Artemether, there may be a few different brand names too.

No kidding, what side effect if I don't mind asking Girlie? Remember you only have to take it for 3-4 days, then 1-2 day break, you can get anxiety and depressed... You can get those feelings being on these drugs, so does primaquine. But I'm telling you, these are the best working drugs I ever used. It may be the anxiety from herxing because it's so severe. Primaquine is the hardest, first cycle I only made it to 12 days. Then 2nd cycle, lol, 7 days, they say you should be on it for 14 days. Turned out to be a humongous stepping stone for me, nothing erradicated the parasites and babesia like these two, nothing...

At one point I took 300mg in one day... I was normally taking 200mg... 100mg x 2 a day

Here's a website that recommends up to 250mg a day... I really think Doctors need to be looking at Babesia as Malaria, possibly worse when you include biofilms in the picture.

https://aac.asm.org/content/46/3/778

https://aac.asm.org said...

0 and 250 mg together

So what happens when you get a dormant strain of Babesia that hides in the liver, include biofilms, then borrelia persisters cells, Bartonella and other coinfections?

A super resistent multi-systemic chronic infection I suspect, but I think we're on verge of a cure soon, in my opinion.

After those, I'd say dapsone, pyramazide, and disulfiram are the second best. Again just from my experience.

We're getting closer, I can't wait to find out how well Tafenoquine is going to working for a lot of you. Exciting times we're living in!

Tafenoquine supposedly to be a one drug for Malaria, lol, I have a feeling it's going to completely eradicate Babesia, even a lot of the biofilms, maybe hit the borrelia too. But you'll definitely have to pair it up with a biofilm buster, Tafenoquine + Stevia together could be very successful treatment. Maybe even Tafenoquine + Essential Oils Oregano or Tafenoquine + Xylitol/Lactoferrin.

Again, I suspect both Doctors and research Scientists have been leaking this stuff to help us... Different way of looking at it right? I think the medical system is so corrupt, going all the way to the head of the CDC, these Doctors and Scientists know this, they're doing everything they can to help us. Just a thought...

There's a war going on for science right now and I suspect there could be some disinforming agents roaming around the forums and social media sites like Twitter, considering what this one doctor commented on ILADs sites. Hey just a theory of mine, I know many of the moderators on Lyme Net have warned Lyme members over the years on those forums. Scary thought I know, just be aware.

https://twitter.com/ilads_lyme/status/1025350772765151232

‏

Dr. Remington Nevin said...

There is no evidence tafenoquine or other 8-aminoquinolines are effective for these indications, and these drugs carry significant risks of iatrogenesis including potentially permanent CNS toxicity. Prescribers should excercise extreme caution in considering any off-label use.

Sound familiar, no evidence?

I think a lot of these Doctors from the IDSA/CDC are shaking in their boots right now, only a matter of time the truth comes out.
https://www.courthousenews.com/insurers-accused-conspiring-deny-lyme-disease-coverage/

I think once the crap hits the fan with glyphosate and Monsanto/Bayer, lyme and the CDC/IDSA, vaccines and the CDC... There could be a whole revamping of the American government and medical system. I could be wrong... But my father who is in his 70s, said he's never seen corruption this bad.

The've lied about everything. Sugar/carbs and fat...

https://www.npr.org/sections/thetwo-way/2016/09/13/493739074/50-years-ago-sugar-industry-quietly-paid-scientists-to-point-blame-at-fat

Sadly not a lot of politicians in my home state have suffered the consequences of trying to privatize the Flint water supply, but I have heard there's a new documentary coming out, that's going to show after they've conspired to privatize and not properly treat the water with the right chemicals, 12 people died and thousands of people infected by lead, they purposedly fudged the numbers to cover it up. https://youtu.be/ztcygor1gq8

I suspect those in our government want to privatize and corporatize everything in this country. And honestly, there may be benefits to privatizing some stuff within the government, but problems come in when there's major conflicts of interest and they put profit over health, and they try to privatize everything.

Post Edited (Charlie55) : 3/24/2019 8:01:10 AM (GMT-6)

Girlie said...
Artesunate and Artemether are different.

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc2014567/

No kidding, thanks for clarifying that Girlie, they're both extracted from the artemisia plant... They probably both have different levels of antimicrobrial and antiparasitic activity against borrelia and malaria.

I’m also wondering about the liver and dormant form of Babesia.

Dr J palpates the abdomen - to feel if there is swelling - can indicate Babesia is still not irradicated.
It’s part of his determination whether or not treatment is sufficient.

He did today when I saw him

Girlie said...
Charlie said: “Do what you can to pass these tips on, it may not get everyone healed, but I believe it'll become a major stepping stone in their treatment.”

I don’t think Dr J will take tips from me who got these tips from a random guy on a lyme forum.

Lol. Probably not. Just for curiosity's sake I will ask Kim F if they have considered primaquine. It is definitely known in the LLMD world, just not used too widely from what I have seen.

Sheekster said...


Lol. Probably not. Just for curiosity's sake I will ask Kim F if they have considered primaquine. It is definitely known in the LLMD world, just not used too widely from what I have seen.

Well I definitely sparked some curiosity from Dr. Hs group after I commented and shared the link to their facebook page, I did talk with someone directly, it's up to you Girlie. I'm pretty positive there's a connection between primaquine and the dormant form of the parasite Babesia in the liver. I've commented quiet a bit on his page before, never had anyone contact me directly before. I'd say they either know bout this, considering ILADs twitter post about tafenoquine or they might of missed it... We'll see how things play out... Could of just been curiosity!
https://twitter.com/ilads_lyme/status/1025350772765151232

Post Edited (Charlie55) : 3/25/2019 8:19:14 PM (GMT-6)

Just a side note, be careful doing marijuana after primaquine. I'm 100% sure Primaquine knocked out Babesia for me, however, the last past couple of weeks of herxing have been hell for me. Even when just taking probiotics or yogurt!!!

I ended up in the hospital these past few days due to insane herxing and schizophrenia thinking the world was ending, doctors put me in the upper psych ward for 3 days, because I was saying crazy crap plus the convulsing and shanking. Sativa Marijuana is probably not a recommended herb to take when you're in the last stages of lyme disease, remember the canninbanioids from this strain go straight to your brain, make you think crazy stuff.

Not to mention coartem/primquine both have their side effects of schizophrenia.

I believe this protocol could be a cure form many Lyme Patients, but if you go on it, it might be good if you have someone that watches you 24/7 so you dont go nuts.

"Sativa Marijuana is probably not a recommended herb to take when you're in the last stages of lyme disease, remember the canninbanioids from this strain go straight to your brain, make you think crazy stuff."

Wow that's nice to know now. I guess it's why I've been hospitalized for that exact reason. And here I thought I just randomly became bipolar all the sudden...