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Posted 8/15/2019 11:37 PM (GMT -5)
Like my progesterone, thyroid, and liver enzymes which are still all messed up. Here are the things that stood out to me:

Thyroid
Triiodothyronine (T3), Free 4.0 pg/mL 2.0 - 4.4
T4,Free(Direct) 0.63 Low ng/dL 0.82 - 1.77

Lymphs (Absolute) 3.3 High x10E3/uL 0.7 - 3.1

BUN/Creatinine Ratio 31 High 9 - 23

Chloride 106 mmol/L 96 - 106 (top of the range - saw it can indicate fluid retention so I included it)

Protein, Total 6.0 g/dL 6.0 - 8.5 (still bottom of the range in spite of high protein intake)

A/G Ratio 2.2 1.2 - 2.2 (no idea what this means but it's at the top of the range)

Bilirubin, Total 1.4 High mg/dL 0.0 - 1.2

ALT (SGPT) 36 High IU/L 0 - 32

Hormones
Progesterone 0.8 ng/mL Ovulation phase 0.1 - 12.0
Insulin 3.4 uIU/mL 2.6 - 24.9 (probably from keto diet)
Estrogens, Total 133 pg/mL 21-30 Days 156 - 350 (low)
Cortisol - AM 14.1 ug/dL 6.2 - 19.4 (taken at 10am)

Mainly my questions are, why is my progesterone so low if I'm on sublingual progesterone nightly, why is my T4 low even though I'm on 2 grains Armour (is it because I'm on a lot of T3?), and why are my liver enzymes and BUN/creatinine (still) elevated? Any thoughts on anything else?

I'm seeing my doc on Monday but he thinks everything is basically normal.
Posted 8/16/2019 12:41 AM (GMT -5)
Thyroid - both FT4 and what part of it converts to, FT3 contribute to thyroid symptoms resolution and TSH feed back loop directive values.

All brands of Pig thyroid have a slightly higher ratio of T3 compared to T4.

If peoples bodies convert really well from t4 to T3, AND they take pig thyroid........you guessed it, their FT3 will be higher in its range than FT4.

Albumin / Globulin ratio:: Types of Proteins. This comes from your liver and immune system. You immune system white blood cell lymphocytes actually influence Globulin levels too. So low CD57, B, T and NK cells can also be responsible for low Globulin test levels. Your liver makes most of the proteins that are found in your blood. Globulin is also usually tested individually. Eating and consuming Protein actually does not change blood protien levels (surprising but true).

Bilirubin, Total 1.4 High mg/dL 0.0 - 1.2 - [https://en.wikipedia.org/wiki/gilbert%27s_syndrome this changes and is influenced by the liver. Can create Jaundice short term: Ive had both. There are genes for this too.
Posted 8/16/2019 12:48 AM (GMT -5)
So is that good news? I'm converting all the T4? It seems strange that would be the case since I am on such a monstrous dose of T3 all told (Armour and liiothyronine combined) but still have a normal T3 lab value. Is the A/G ratio anything to be noted or just a glitch so to speak? Do you believe I have Gilbert's syndrome?
Posted 8/16/2019 12:56 PM (GMT -5)

jb1994 said...
So is that good news? I'm converting all the T4? It seems strange that would be the case since I am on such a monstrous dose of T3 all told (Armour and liiothyronine combined) but still have a normal T3 lab value. Is the A/G ratio anything to be noted or just a glitch so to speak? Do you believe I have Gilbert's syndrome?

Or possibly the opposite............if you don't absorb T4 very well- so its low, and the higher T3 is mostly from your pig thyroid med.

T4 med binds to any protien (rendering it useless) it encounters in the digestive tract.......thus take away from food and dont eat protien till about 1 hr after and be consistant with this. T3 does not bind to protien.

Several possibilities or all combined.

Why are you on so much T3? High T3 doses are for treating reverse T3,......did you have that condition? If not,...remove the extra T3 and up the Armour.

Taking this sublingual (Canadian ERFA thyrid and US Acella NP thyroid) will avoid the protien binding issue. Armour and Nature Throid apparently need to be chewd up a littlle as they dont break down well with saliva.

If you get immune cells testing and its low......thats prob the A/G ratio showing up.

dont worry about gilberts, I have that too, but the repeated test results changes with me.
Posted 8/16/2019 1:26 PM (GMT -5)
Re- Gilbert’s

I was diagnosed with it in my teen years.
This was because my eyes had a yellow tinge to them for a period of time.

Interestingly - after some treatment for lyme/bart my bilirubin went down - and stayed down for several months . I do wonder if my high bilirubin has always been from a smouldering bart infection that I had contracted as a child.
I have had healthy life prior to lyme - athletic, rarely sick but had a few health anomalies along the way.

Haven’t tested it lately .
Posted 8/16/2019 8:06 PM (GMT -5)
I do take it away from food by at least an hour. I am on a high dose because I have trouble keeping my weight down and my doc thinks my metabolism is messed up. I believe histamines are a major factor causing this though. I'll ask about Gilbert's syndrome but it doesn't sound like it's anything to worry about then. I wish I knew why my histamine reactions are so horrible. Restaurant put soy in something yesterday without telling me and I was itchy and burning skin all night, woke up and joint pain and anxiety plus more weight gain...ugh. Wish I didn't have to eat anything at all sometimes.
Posted 8/17/2019 9:53 AM (GMT -5)
Let me clarify this:

The main thing I see though, is your taking additional T3, when your T3 levels are already higher in range compared to T4. This does not make sense.

As you might know (?), your natural pig thyroid already has more T3 in it, compared T4 to begin with, no need to take more.

The only reason to purposely aim for higher ratio T3 is if one has whats called reverse T3, which Im assuming you dont have- no mention of it.
Posted 8/17/2019 8:27 PM (GMT -5)
I'm not sure, my doc explained it to me but he said he wanted me to go up on T3 before I go back down. I wish I could give an explanation but it made sense at the time.
Posted 8/17/2019 11:01 PM (GMT -5)
jb - you mentioned anxiety - T3 can cause it - or did you have anxiety prior to adding the T3?

And I wouldn’t worry about the Gilbert’s syndrome - especially if your other liver function tests are good.
Posted 8/18/2019 8:27 PM (GMT -5)
Yes I know T3 can cause it but it has been a problem for a long time...it's really not bad, it's more caused by my symptoms and being unable to deal with them than anything... and it's weird, one of my liver labs is always fine and the other is always bad. The thanks I get for avoiding alcohol all of my youth.
Posted 8/19/2019 6:11 PM (GMT -5)
Hye JB - did the tests include a complete comp panel? Creatinine, EGFR, potassium, sodium, etc...? The BUN/Creatinine makes me wonder if all the electrolytes and other kidney numbers were included. It would make sense if they were. With a BC Ratio high, the other tests included on a comp panel would tell more of a story.

I can't remember all you are treating Lyme with. Could be impacting it all.
Posted 8/19/2019 8:22 PM (GMT -5)
Yes creatinine was normal, GFR, potassium, sodium all normal. And no problem for not remembering, I can't keep track of everyone on here either. I am using antibiotics and Buhner immune support for Lyme.
Posted 8/20/2019 9:25 AM (GMT -5)
From dealing with kidneys, I have been told high BUN/Creatinine ratio can be caused by high protein intake or thyroid problems, which you mention.
Posted 8/20/2019 8:35 PM (GMT -5)
Hmm. Well I do have thyroid problems but they're being medicated, and I don't think I'm taking in a drastic amount of protein. Maybe just idiosyncratic. It was high last time too.
Posted 8/20/2019 11:47 PM (GMT -5)
I have similar elevated BUN/creatine ratio to yours, and it went up with extra protien intake even though serum protien remained low like yours.

Dr said in order to see if it was cause by extra protien supplementation- i'd need to be off it for one month.
Posted 8/21/2019 8:17 PM (GMT -5)
Ah alright that must be it. I'm surprised he didn't catch that since he's the one who recommended keto.
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