Minocycline vs Doxycycline

Doxy is harsher than minocycline.

But I still wouidnt lay down soon after taking mino.

I found mino gave me more head stuff - I didn’t notice doxy even affecting my head.

After awhile on the mino, the head stuff got better.

As it was explained to me doxycycline directly irritates the esophagus as does tetracycline to a lesser degree. Laying down after taking it would only make the condition worse. I know one pharmacy told me to try and stay upright for two hours. And yes intracranial pressure is another side effect as well. I could never tolerate Doxy as I felt like I had constant severe heartburn....just my experience

i got terrible staining on my teeth from Mino. I got brown spots all over them and when i used to laugh you would think i've been eating chocolate all day
besides that, i got skin staining just below the eye, not big but visible, a brown spot that appeared while treating.

My dentist was able to remove the teeth staining using the ultrasonic scaler used to remove plaque... but it took hours ... anyway, all spots are gone now ...

nevertheless, i think mino treatment was really essential for my progress, since it has such good BBB penetration. so i recommend it over doxy. mino also gave me no GI issues.

doxy was harder on GI than mino, i remember.

I got brown stains on my teeth from rifampin. Minocycline caused some slight discoloration, but it wasn't as bad.