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Lowering Cytokines Question

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Posted 3/10/2020 2:17 PM (GMT -5)
I'm on month 4 of Azithromycin/Tinidazole combo and have finally have gotten an indeterminate result on my last IGX test. I've tested positive on the 4 tests prior. I currently only take a multivitamin along with Sacc B. Is there anything else I should be taking? Something to help lower cytokines? I've read liposomal gluthathione can help. Can this be taken long term? Most of my symptoms are neurological. Brain fog, forgetting words, facial twitching, depression, irritability, poor sleep.
Posted 3/10/2020 5:26 PM (GMT -5)

Xabian said...
I'm on month 4 of Azithromycin/Tinidazole combo and have finally have gotten an indeterminate result on my last IGX test.

Repeated testing for the infections isn't a good measure about whether there is still active infection.
Posted 3/11/2020 4:30 AM (GMT -5)
What you eat can increase or decrease oxidative stress. You should keep a food log with what you eat and how bad your symptoms are. You can often see the direct correlation between what you eat and what is causing more problems. Be sure to go back at least 3 days to see the secondary food allergies like dairy. This can limit oxidative stress as much as anything.
Posted 3/11/2020 8:59 AM (GMT -5)
Agreed, testing is not a way to measure progress. Once you have had these infections, you may always test positive for IgG. How are your symptoms - any improvement after four months?

There are a great many ways to lower cytokines. Here's what MR has to say about it:
https://www.treatlyme.net/guide/cytokines
Posted 3/13/2020 9:05 AM (GMT -5)
Things I know about that may help with cytokines - EPA/DHA (fish oil), Chinese skullcap. Metagenics has an expensive supplement called SPM Active that has helped me in a storm before. I took 4 capsules at a time. You want to increase antioxidants. Like Georgia said, food can help or hurt. Avoid foods that are inflammatory for you. Eat vegetables and fruits that aren’t inflammatory and have nutritional value.

Detoxing should help, as well. Toxin buildup will increase inflammatory response. Epsom salt baths, sauna, coffee enemas can help move toxins out of the body. TUDCA Plus has noticeably helped my detox capabilities in ways I don’t understand. All I can say is it’s been a game changer for me. It helps the liver.

Post Edited (WalkingbyFaith) : 3/13/2020 8:14:47 AM (GMT-6)

Posted 3/13/2020 9:14 AM (GMT -5)
You asked about glutathione. Glutathione and NAC can both help but should be started low to see how it affects you. Glutathione will cause your body to “dump” toxins that are stored in various places and will increase oxidative stress until those toxins are removed from the body. Binders are often taken to help bind the toxins and exit them via the GI tract. Binders make a world of difference to some and not much difference to others.

NAC can help your body’s ability to produce glutathione and has other benefits. NAC is beneficial, IMO, even if you don’t feel the effects. It can cause a herx, so start slow. (It helped my cognitive functioning when I first started it, and then plateaued.).

Alpha lipoic acid (ALA) also helps the body’s ability to produce glutathione. I believe Buhner indicated that ALA was more helpful than NAC. ALA can help with detox, but it is contraindicated if you have mercury amalgams or mercury toxicity, according to Andy Cutler. I have experienced adverse effects from it in that regard myself.
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