.

CFS often involves some sort of mitocondrial dysfunction.

Have you tried CoQ10 and LCar?

In addition, and in the same vain, methylation often plays a role. 70% of your SAMe goes towards making creatine for ATP/energy production. I've actually found creatine to be one of hte most helpful supplements for me. It increases my energy levels and stamina on runs (even though historically its more been used for anaerobic exercise not aerobic), and since you dont need to make as much ATP it leaves SAMe for other uses like neurotransmitter methylation and dna repair. This has been more helpful than methyfolate for me, which I cant tolerate.

Finally, an infection can often trigger it, but its not always one of the BBBs. I've seen a lot of people on the PhoenixRising blog attribute it to reactivated EBV, and one guy claims his (infected) root canals were causing his, and he had a dramatic return to health after dealing with them.

Post Edited (dcd2103) : 4/14/2020 11:33:26 AM (GMT-6)

I never had very low levels of energy but low level laser therapy increased mine. Cbd oil also but a bit less. DNRS have helped some with fatigue also.
My girlfriend had a huge increase after starting with autoimmune paleo. Before that she was in bed 20 hours a day and made huge improvements.

Low level laser therapy is a laser that I use in the nose for 25 min a few times a week.
It is supposed to help with the immune system. I bought it after reading a thread at Phoenix rising where people with ME/CFS got more energy after using it.
https://vielight.com/devices/vielight-655-prime-systemic

Astro what did you suddenly suspect was happening?

I have chronic fatigue as well. Very tired all the time. Gets worse with abx.

I had major fatigue as well, - it was from many things combined though. Ive power napped my whole life after adolescence - when ill, I had to do this several times a day.

Always had jobs with minimal supervision and flex time for this reason - , napped in the car off site lunches ect, no choice, i literally adapted my life around fatigue. Also surprisingly competed in endurance sports (with good results) but was trained how to mentally control Adrenalin/cortisol release as it pertained to physical endurance. It worked, but I would be completely "done" (zombie in a coma) at the end while others were energetically socializing. I could hardly talk coherent until a hard power nap after the event.

My case:

-These infections cause obviously major body stress.
-Adrenals over worked- takes years to heal, im prob at 80-90% there.
-hashimoto autoimmune (lethargic), then ten years of the wrong thyroid med after Hashi Dx
-introvert- groups of people wear me out
-past diet , although not bad, was cytokine releasing per my food/blood tests

A lot better today,but stress or to many people will still tire me out (which is not an illness), a 10-30 min power nap after work sometimes is needed and im good to go. The autoimmune thing may never go away- its controlled(by diet and health) at the moment for last two years, but still there.

Post Edited (astroman) : 4/23/2020 12:39:12 PM (GMT-6)