Lyme Disease is a False Case Definition, and is Really Lyme Borreliosis Relapsing Fever

Why did mods lock and delete this post?

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Long-term antibiotics did not work for me, for some, they do; maybe they find remission, but I had little success taking long-term antibiotics. I am not denying that long-term antibiotics can work, only that the disease process of persistent Borreliosis ie., the low antibody patients who are unable to test positive on the falsified ELISA screenout test, the sickest of patients, as I am, have post-sepsis and the tolerization of our immunesystems.

What are Osps?
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They are Pam3Cys; the blebs that are shed by borrelia to evade the immune system are covered in Outer Surface Proteins, or Osps, such as OspA, OspB, OspC, and so on. These Osps are characterized by their chemical structure as "triacyl lipoproteins". In organic chemistry, structure equals function. Here we will explain how the Osps function to cause disease.

See the illustration below which shows the chemical structure consisting of three acyl groups on one end of the molecule. The chemical name is "Tripalmitoyl cysteine", abbreviated as Pam3cys, or sometimes P3C. It's easy to see the three acyl groups: the three zigzag lines that are labeled in red. These acyl groups are fatty acids and are what make OspA and other borrelial Osps immunogenic and also damaging to the immune system.

https://static.wixstatic.com/media/47b066_cb3b18ed64e84e45bb7067a039431786~mv2_d_3282_1734_s_2.png/v1/fill/w_519,h_276,al_c,usm_0.66_1.00_0.01/47b066_cb3b18ed64e84e45bb7067a039431786~mv2_d_3282_1734_s_2.png

Pam3Cys is a potent endotoxin
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Triacyl lipoproteins are managed by toll-like receptors 2 and 1, together (TLR2/1), in the human immune system. The TLR2/1 "heterodimer" also manages antigens associated with fungi and lipoproteins from other microbes such as E. coli, tuberculosis and MRSA, to name a few. Triacyl lipoproteins are used in laboratories to induce experimental sepsis. Fungal antigens are known to cause severe neurologic disease.

​In 1998 a synthetic OspA product was approved for use as a vaccine known as LYMErix. It was pulled from the market after three years due to numerous reports of severe adverse events, which is not surprising considering the damage a triacyl lipoprotein is capable of doing. For starters, it can damage the brain.

​OspA (Pam3Cys) causes brain inflammation, whilst at the very same time causing tolerization of the immune system and anergy
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Mario Philipp of Tulane University reported that OspA causes astrogliosis: pathological changes that take place in the brain as a result of damage or disease. Robert Martin & Adriana Marques of the National Institute of Autoimmune and Infectious Diseases (NIAID) reported that OspA causes brain inflammation while humoral immunity is blunted:

​"These results show that signaling through TLR1/2 in response to B. burgdorferi can elicit opposite immunoregulatory effects in blood and in brain immune cells, which could play a role in the different susceptibility of these compartments to infection."

​There is abundant research describing mechanisms of immunosuppression by Borreliae and their lipoproteins. The sickest of patients are thus those who have a compromised immune system and thus have pooer outcomes.

Dattwyler, Raymond J., some contend a fraudster, owns a patent that describes OspA as Pam3Cys. Therefore the Lymerix vaccine could not have been a blood-stream-injected “vaccine,” because it is a human TLR2/1 agonist. This Dattwyler patent is for an inhalation form of OspA/Pam3Cys. Lung immunity is different from injecting fungal antigens directly into the blood.

(US20090324638) LIVE BACTERIAL VACCINE
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Somebody said...
"A lipidation/processing reaction has been described for the intact OspA gene of B. burgdorferi. The primarytranslation product of the full-length B. burgdorferi OspA gene contains a hydrophobic N-terminal sequence, of16 amino acids, which is a substrate for the attachment of a diacyl glyceryl to the sulflhydryl side chain of theadjacent cysteine (Cys) residue (at position 17). Following this attachment, cleavage by signal peptidase II and
the attachment of a third fatty acid to the N-terminus occurs. The completed lipid moiety, a tripalmitoyl-S-
glycerylcysteine modification, is termed Pam3Cys (or is sometimes referred to herein as Pam(3)Cys or
Pam3Cys). It has been suggested that the lipid modification allows membrane localization of proteins, with
polypeptide portions exposed as immune targets. In addition to serving as targets for the immune response,
Pam3Cys-modified proteins, such as OspA, have been reported to act as potent inflammatory stimulants though
the toll-like 2 receptor mechanism (TLR2).”

http://patentscope.wipo.int/search/en/detail.jsf?docid=us42934470&recnum=9&maxrec=30&office&prevfilt
er&sortoption=pub+date+desc&querystring=tripalmitoyl+cysteine+or+pam3cys+and+epstein-
barr&tab=nationalbiblio

Therefore, the crime is Lyme Disease. Alan Macdonald understood this samantic game. CAlling it Lyme Disease plays into the hands of the fraudsters who falsifed the case definition back in the early 90's. Lyme Disease is LEGALLY simply a bad knee HLA-response whilst the sickest of patients, those with low-antibody counts are thrown to the curb.

Take back truth and call it Lyme Borreliosis. They understand the samantics game they created, and we must too.

astroman said...
"Why did mods lock and delete this post?"

I didnt read it, but if a post is "politically raged" or political anything, as others here have done before, it will sometimes go away.

"Lyme Disease is a False Case Definition, and is Really Lyme Borreliosis Relapsing Fever" -

Mmmm, ok, but half the LLMD's or patients dont really care what its called. They want symptom relief, not English class. "Chronic lyme" is good enough for most.

They sometimes dissapear? Well this post isn't politically chraged, it is from someone who sufferers from Borreliosis and whose life has been changed because of the falsification of the case definition. No politics involved in justice.

Half the LLMD's might not care and more than half the patients might not care either about what term we use, but I as a patient do care; likewise egal matters and truth tell us we should care. Some of the same people who fronted the Lymerix scam, falsifying the diagnostics; you know, the same ELISA screen out test we use today, the one that is 15% accurate and throws out 85% of the sickest of patients who do not reach the antibody cutoff range due to the raising of the cutoff range by defrauders, are now fronting Lyme activist institutions, like the Lyme Working Group.

What EVERYONE should know here is that if you have acute symptoms and you do not test positive on the ELISA, order an IGENEX test. If band 41 is positive. Then you have lyme Borreliosis. It's doesn't matter if your Igenex and CDC negative. band 41 is all you need, just rule out Syphilis.

Justice must be served and truth must be revealed so that we can find closure. No lawsuit will win if we use the term Lyme Disease. We must use the term Borreliosis and look back at the studies showing OSPA's immuno-supressive nature.

"Chronic lyme" is good enough for most."

It isn't good enough in a court of law; that's why the criminals who fronted the Lymerix scam are still practicing and patenting VBDs despite their color of law violations. Persistent or even Chronic Borreliosis is the right term to use, if one wants to file a law suit. They will laugh us off if we say we have Lyme Disease, because Lyme Disease is their false case definition of a HLA-linked high antibody result.

Post Edited (birthdaysuit) : 5/5/2020 3:56:12 PM (GMT-6)