Persisters (Rawls protocol?)

So, I’m currently weening down off IVIG (will make a separate post another time) after a year and have been taking Bicillin LA every 5 days for 1.5yrs (works wonderfully) and trying to do the Gupta program/DNRS for 15 mins each day. The success of the bicillin leads me to think my last remaining symptoms (dysautonomia) may be caused by Lyme (likely) persisters or perhaps some stealth Bart (unlikely). My symptoms were always based in my brain (psych, neuro) so I need supplements that will cross the BBB - I recently added Allicin (using Allimax 1x a day for now, think it’s 180mg) and oil of oregano about 10 days ago. Also had hout, sida, and Jk lying around from the last few years so I started those in the past 3 days. Have definitely noted an uptick in the pots/anxiety since starting the Allicin garlic and Oregano (it’s from a local store but has caravgral (sp?) in it).

Anyways, on Dr Rawls website, for Lyme/Bart persisters he recommends:
1) Liposomal Cinnamon Clove & Oregano Oil. Take one pill two times a day. I prefer the Doctor Inspired Formulations product called Liposomal Cinnamon Clove & Oregano Essentials
2) Cryptolepis Tincture. Work up to 5 ml (1 tsp) 3 times a day over three weeks by starting at 5 ml 1 time a day, then 5 ml 2 times a day, then 5 ml 3 times a day.
3) Japanese Knotweed. Work up to 1.25 ml (¼ tsp) to 2.5 ml (½ tsp) 3 times a day over a 3 week period of time.
He also mentions methylene blue pills but I’m not particularly interested in that.


I ordered the liposomal cinnamon/oregano brand he recommended and have Jk on hand so I’ll try those 2 and continue along with the Allicin garlic, hout, and sida to see what happens. Hopefully I can tolerate the liposomal stuff (everything else I can handle just fine currently).

Anyone have experience with Rawls protocol, the liposomal cinnamon/oregano product or just fighting persisters in general? If it isn’t persisters that are causing my last lingering system then I’m pretty sure I’ve reached my max potential.

persisters do not seem to exist in isolation - the papers i read on lyme persisters are intriguing and talked about populations in stationary growth phase actually consisting of heterogenous mix of persister and non-persister forms with apparently some of each population dropping into and out of the different forms and states over time - but at the population level absolute numbers remaining fairly constant

its quite odd stuff to get your head around - especially when you start to consider what each individual bacteria is doing - dormant, active, reproducing/divining/dying, dormant again ...?

acc to the leading scientists on the topic - the jury is still out on whether Bartonella truly forms persisters - as opposed to simply stationary growth phase - despite the Zhang papers using persister terminology when discussing Bartonella ....

Dr J talks about a strategy of actually using specific antibiotics to drive lyme spirochetes into cyst forms - and then using drugs active against cyst forms to kill them (pulse tinidazole or metronidazole)

ref liposomal vs regular forms of oregano oil - Dr SP says that he prefers the liposomal forms of essential oils (he uses oregano) because the normal forms are hard on the digestive system in the doses needed - in liposomal forms - due to the much better absorption - the dose is much lower - and hence easier on the stomach.