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Is nystatin effective with antibiotics?

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Posted 8/16/2023 6:55 AM (GMT -5)
Do you guys think it's possible to keep candida under control while taking antibiotics?

I'm taking 2m units a day and hoping it's keeping things at bay but I'm honestly not sure.

I guess the question is, do you think candida can be controlled/beaten back while on antibiotics?

I'm back on mepron/zith and having a hell of a time and could use the support. These meds are hitting me in my jaw bones, my legs, my shins, my ribs, 15 years of Bart and company this stuff seems to be everywhere now.

I know I just have to keep going.
Posted 8/16/2023 8:25 AM (GMT -5)
I don't know if nystatin alone is effective, especially since (at least in the US) so many strains of candida are resistant to it.

Are you also taking probiotics and/or consuming probiotic foods and drinks (at least two hours away from the antibiotics) in order to maintain some healthy flora that can outcompete the stuff you don't want to overgrow?

Keeping your diet sugar-free and low in carbohydrates for the candida to eat also can help.

There are also herbs that might keep candida in check, like pau d'arco, caprylic acid, grapefruit seed, olive leaf, oregano, garlic, and berberine.
Posted 8/16/2023 8:44 AM (GMT -5)
fluconazole is the other anti fungal often used

there is pretty good evidence it has activity against bart also - so could be helpful
Posted 8/16/2023 9:59 AM (GMT -5)
Thanks guys.

Fluconazole is getting added and the herbs I can't tolerate too well at the moment but have and will take again.
Posted 8/16/2023 10:51 AM (GMT -5)

DerekF said...
Thanks guys.

Fluconazole is getting added and the herbs I can't tolerate too well at the moment but have and will take again.

some LLMDs use it only a few days a month ( 2 to 5 days ) to keep candida at bay

so that might be an option to reduce additional herx - while still doing the antifungal job

i second the above advice of low carb - it seems the way to go for lyme and bart in any case - helps all around
Posted 8/16/2023 11:46 AM (GMT -5)
Fluconazole is way more effective than Nystatin.

This and lighter on carbs and nothing with added sugar is an effective plan for gut candida- (been there several times). I used the usual anti-candida herbs on my own till they were no longer effective, then went with the RX.

You can herx on Fluc. I got waves of hot and sweaty from it, some disturbed sleep in addition to the normal lyme disturbed sleep.

While on this with ABX, get your liver enzymes tested (alt, ast?) if using longer than four weeks. They will rise, then should normalize. Dont want them more than double your baseline though. This is what knowledgeable LLMD's follow.
Posted 8/16/2023 8:52 PM (GMT -5)
Severe herxing can weaken your immune system and leave you vulnerable to other infections including candida.

Mepron is usually a fairly effective anti-fungal by itself. Are you having problems with candida while taking mepron?

You can try fluconazole, but watch out for the adrenal and potassium effects.
Posted 8/17/2023 1:14 PM (GMT -5)
Is it logical that 100mg fluconazole daily with 250mg x2 zith would be adaquate to combat fungal overgrowth? Assuming it is already an issue before starting the therapy, but attempting to treat both simultaneously.
Posted 8/17/2023 1:51 PM (GMT -5)
I may still have my expired bottle of Fluc. I will see what mg it was.

But, I was not using this as a deterrent (not its intention).

My dose was high enough to eradicate positive tested Candida Albicans which I acquired while on ABX.

Post Edited (astroman) : 8/17/2023 10:55:29 AM (GMT-8)

Posted 8/17/2023 2:05 PM (GMT -5)
I'm assuming it will be sufficient.

I have aggressive bartonella that has to be treated with antibiotics, I can take the fluconazole up to 200mg once tolerated.

I know many docs will use it indefinitely with antibiotics with good success.
Posted 8/17/2023 2:58 PM (GMT -5)
"I know many docs will use it indefinitely with antibiotics with good success"

Just cause a Dr will do it, doesn't mean its all that safe. Longest I did was two months of it. After I tried everything else for Candida.

Its harder on your body than antibiotics, thus my mentioning liver enzyme testing with use of Fluc.
Posted 8/17/2023 4:05 PM (GMT -5)
yep - liver function testing periodically - each month - if on it longer than a couple of weeks is advised - as Fluconazole is known to cause liver damage in some - and so you need to know and discontinue if it does

hence the regular safety labs
Posted 8/18/2023 4:30 AM (GMT -5)
Thanks guys!

I get labs at least once a month, they've somehow never been too off.
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