I really stopped going down the Diagnostics train recently.

Keep in mind that a Diagnostic only benefits If a Treatment can evolve from it (or so i think)

While its interesting finding Out whats going on, its really crucial on what to actually do with this information to get better. Here in Germany we have a massive Problem with a dysbalance in spendings on Diagnostics vs Treatment.

Sorry for being so pessimistic

I don't really know much about CDR but I do have absent GSTM1 gene (I think this is when you get a mutation from both parents) and a mutated GSTP1 gene and glutathione has been life changing for me.

This is what it says with my results incase you are interested

The GST isoforms (M1, P1, and T1) are more or less prevalent in various tissues; all catalyze the conjugation of electrophilic compounds with glutathione. Defects in GST activity can contribute to fatigue syndromes, and to
various cancers throughout the PHASE II Detoxification: Conjugation of Toxins and Elimination In Phase II detoxification, large water-soluble molecules are added to toxins, usually at the reactive site formed by Phase I reactions. After Phase II modifications, the body is able to eliminate the transformed toxins in the urine or the feces (through the bile). body.

Glutathione-S-transferase detoxifies many water-soluble environmental toxins, including many solvents, herbicides, fungicides, lipid peroxides, and heavy metals (e.g., mercury, cadmium, and lead). The various forms of GST work together to eliminate toxins. Decreased glutathione conjugation capacity may increase toxic burden and increase oxidative stress.

Health Implications: Glutathione S-transferases (GST) are responsible for detoxifying certain products of oxidative stress and a variety of electrophilic xenobiotics and carcinogens such as solvents, herbicides, pesticides, polycyclic aromatic hydrocarbons, steroids, and heavy metals. GSTM1 is located primarily in the liver, whereas GSTP1 is located primarily in the brain and lungs. When there is no gene present on the GSTM1 chromosome it is called an "absent" allele. This results in reduced capacity for hepatic detoxification and increased risk of various cancers, chemical sensitivity, coronary artery disease in smokers, atopic asthma, and deficits in lung function. Risk appears reduced for colorectal- and head & neck cancer, but only when cruciferous vegetable intake is high. GSTP1 polymorphisms are associated with either higher or lower enzyme activity, depending on the exposure. This GSTP1 polymorphism is associated with increased risk of various cancers, risk that is compounded by exposure to cigarette smoke and the "absent" GSTM1.

Minimizing Risk: Minimize exposure to cigarette smoke, charred food, herbicides, fungicides, insect sprays, industrial solvents, and toxic metals. Ensure availability of glutathione (GSH) precursors and cofactors, e.g., methionine, N-acetylcysteine, glutamine, glycine, magnesium, and pyridoxal-5-phosphate (B6). GSH depletion may be offset by alpha lipoic acid, milk thistle, and taurine. Allium vegetables (e.g., onions, leeks, garlic) and crucifers (e.g., broccoli, cauliflower, cabbage, kale, Brussels sprouts, radish sprouts) can increase GST activity and reduce cancer risk. Consume an antioxidant-rich diet to prevent oxidative stress.

These are the supplements my doc recommended based off those results:

~l-Methionine 375mg 60caps (PureEncap)
Take one cap daily
~NAC (N-Acetyl Cysteine) 600mg 60caps (Solgar)
Take one cap daily
~l-Glutamine 500mg 90caps (PureEncap)
Take one cap daily
~Glycine 500mg 180caps (PureEncap)
Take one cap daily
~MagMind (Magnesium L-Threonate) 90caps (Jarrow)
Take one cap twice daily
~P-5-P (Pyridoxal 5’-Phosphate) 30mg 100caps (Klaire)
Take one cap daily
~Glutathione Reduced 500mg 60caps (Jarrow)
Take one cap daily
~Alpha Lipoic Acid 600mg 120caps (PureEncap)
Take one cap daily
~Silymarin 250mg 120caps (PureEncap)
Take one cap daily
_Taurine 1000mg 100caps (Jarrow)
Take one cap daily