glad to hear you are doing OK WBF
thanks for the reminder of Alinia as a potential way to calm down a flare
i seemed to recall reading that some people believed it had anti-borrelia activity and also antiviral activity
i think the anti-borrelia activity was from unpublished work by Alan MacDonald mentioned by Dr SP
i had thought the antiviral effects were largely anecdotal - but i did a quick google search and was surprised to find quite a bit of published work on it as a broad spectrum antiviral - so its quite an interesting drug with a nice long history of safe use
paper said...
Nitazoxanide inhibits a broad range of influenza A and B viruses including influenza A(pH1N1) and the avian A(H7N9) as well as viruses that are resistant to neuraminidase inhibitors. ... Nitazoxanide also inhibits the replication of a broad range of other RNA and DNA viruses including respiratory syncytial virus, parainfluenza, coronavirus, rotavirus, norovirus, hepatitis B, hepatitis C, dengue, yellow fever, Japanese encephalitis virus and human immunodeficiency virus in cell culture assays
https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7113776/and even some specific studies of its direct activity in Canine parvovirus
another paper said...
Three drugs-Nitazoxanide, Closantel Sodium, and Closantel-with higher anti-CPV effects were further evaluated in F81 cells by absolute PCR quantification and indirect immunofluorescence assay (IFA). The inhibitory effects of all three drugs were dose-dependent. Time of addition assay indicated that the drugs inhibited the early processes of the CPV replication cycle, and the inhibition effects were relatively high within 2 h post infection. Western blot assay also showed that the three drugs had broad-spectrum antiviral activity against different subspecies of three CPV variants.
https://pubmed.ncbi.nlm.nih.gov/31412574/of course - most antivirals work best if taken early in the course of the infection - and we don't know exactly if the symptoms 4 weeks down the line are due directly to ongoing viral replication - or some legacy effect happening downstream - but it seems worth a try.
in fact i had tried a 5 day course of alinia a few months ago - and had an unexpectedly strong herx effect from it - which included pain all over my body in muscles and joints - but also had some useful improvement in the weeks following that - which i wondered might have been attributable to the alinia - so it has been on my list to try again for this reason also.
its very broad spectrum - being active for many protozoans, slow growing anaerobic bacteria and viruses
i started 500mg 2x a day from this morning and will report back