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MRI with contrast question?

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Posted 4/11/2014 5:43 PM (GMT -5)
Anyone ever hear of the contrast agent(gadolinium) causing a psa spike? I had a MRI about a month ago and recently had an increase in psa from 2.7 to 3.5 (while on Avodart). Probably not related, but just thought I would ask. May be time to abandon A.S.
Posted 4/11/2014 7:28 PM (GMT -5)
I don't remember it ever being brought up while I have been here, but others might have more info. Good luck and keep us posted.
Michael
Posted 4/11/2014 11:12 PM (GMT -5)
I had a spike after MRI. Quite a big one.

My uro ignored it too. Just wheeled me into OR and had his way with me.

Haven't been the same since.
Posted 4/14/2014 11:00 AM (GMT -5)
Thanks for the reply Havanon, how long after the MRI did you have the psa test and how large a spike was it?
Posted 4/14/2014 11:31 AM (GMT -5)
I had had many MRI's done with that contrast agent, and it never caused a PSA spike or uptick with me, whether I still had my prostate (long gone) or since. This is a new one to me.

D.
Posted 4/14/2014 12:00 PM (GMT -5)
David, I'm just grasping at straws. I recently had the mpMRI, with fairly good results (did find small < 1cm area consistent with g6) and I felt fairly comfortable staying on A.S. Then almost a month later I get this psa spike that had been fairly stable the two years I've been on AS. I was hoping to stay on AS, but it seems I always have something to cloud my judgement.

Thanks for your reply.
Posted 4/17/2014 7:32 PM (GMT -5)
It was a week or so, jvm. It doubled over the month. But my cancer is aggressive I'm told. Even so it is a big spike.

Maybe the MRI does spike the PSA but never mind. Have another PSA test. What the heck have a biopsy. And if you must have the thing cut oUT then join the crowd
Posted 4/17/2014 8:28 PM (GMT -5)
Wouldn't happen to spike because of the fact then stuff that coil up there and I can imagine it doesn't push on your prostate?

I only am mentioning it because I have that scheduled again. I was not thrilled about it the first time. Now I have a reoccurrence so they are doing some of the same tests again.
Posted 4/17/2014 10:32 PM (GMT -5)
Hey thanks for the replies.

Havanon
I'm trying to avoid joining that part of the club.

NavyChief
Sorry about your reoccurrence, what was your primary treatment?
Posted 4/18/2014 9:16 PM (GMT -5)
Surgery. Had a 1mm positive margin a little over a year ago
Posted 4/18/2014 10:14 PM (GMT -5)
Chief, sorry you had to deal with this at such a young age; are you still in the Navy? I was in the Navy some years ago( like 43 or so)
Posted 4/19/2014 2:38 AM (GMT -5)
I've had a handful of the endorectal coil MRI's with contrast. Have not noticed a spike in PSA but now that prostate is gone I'll be watching. Just had labs, then the MRI yesterday so ill look for the PSA values next month. I usually have this test the same day as C-11 Choline PET so any variation may not be decisive on the cause...
Posted 4/19/2014 6:45 AM (GMT -5)
I would see what the PSA value is again in 3 and 6 months before abandoning A.S. What does your Urologist think?  My A.S. Dr. at Memorial Sloan Kettering recommends the PSA taken every 6 months (not 3) because of this fluctuation.
Posted 4/19/2014 8:59 PM (GMT -5)
I am still in. I am coming up on 23 years. :-) Yea it does suck. I keep thinking I am way too young for this crap
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