Posted 6/1/2014 12:44 PM (GMT -5)
As you might know been involved in high risk PCa case from day one in 2002. Started with Zoladex (uro-doc), then I got further opinions and added casodex and proscar to get to ADT3 combo, figured Dr. Leibowitz might be right on hitting it hard asap. Well the ADT3 was failing after around 14 months, I took it for 2 years and monitored psa monthly or sometimes even more often. I had 8 consecutive raises while on ADT3, although small numbers....still shows it was failing. Switched to DES 1 mg. worked very well, dropped psa and stabilized and used over the next 8 years, then signs of failing.
After failing on that used many protocols in short time frames to see if psa results were happening. So tried Keto low dose and high dose, tried Keto+Leukine+Estradiol patches (found out I had reactions to Leukine which is more rare, so dropped that one). Tried casodex+DES and it did have results for maybe 2 months or also did slow increases. Tried Eulexin and it didn't do anything worthy, but worth a try. Tried estradiol patches plus Dexamethasone (aka Doug's protocol as in Paact Newsletter), however did not work for me but is working great for Doug even after 15 months or so. Tried DES again and no luck, so moved onto Zytiga and it was working for months and may still be useful, switched to Xtandi because I had a chance to try it actually for free (don't ask don't tell) and it is working apparently, but could work better.
Since mentioned on the forum Prednisone is used with Keto or Zytiga, I only used 1/2 dosage level on Zytiga without issues and weaned off of it myself with about 12 days (cutting the pills down). I also, switched from Prednisone to Dexamethasone cause I had it here, they are comparable but Dexa pill of 1 mg= 6.6 mg of Prednisone (fyi). I think I preferred Dexa and slept better using it vs. Pred., best I can tell anyway. Not recommending 1/2 dose on Pred. or switching to Dexa without your doc, but it did not seem to make a big deal that I know of in my usage. I can tell you that DES 1 mg served me well, built bone density and gave a long remission and cost nothing (no patents) and I felt way better on it than any other drug therapy I have used. Funny how it is considered junk by many. Oh, I also take 3 Xtandi pills or was using less on Zytiga too but adding food which is said to increase its effectiveness. Well that's my story, did also try or trying some unlisted items and that is another story, probably not worthy of print (lol).