Hi hrpufnstuf, - I think you MAY be misunderstanding what was meant. I believe that, probably, the PA meant to convey to you that the Cipro is not an effective antidote against whatever it is that is most likely to be causing your elevated PSA or is most prevalent, not that you, as an individual is resistant to Cipro.
Unfortunately, the more antibiotics are used, the more they adapt resistance to effective antidotes. Bacterial Infections are often able to be detected by growing a sample (swabbed, urine, blood, etc) in a petri dish(s) in the LABORATORY and applying individual antibiotics to them, to determine which is most treatment effective, or prophylactically protective, against a particular infection.
If Cipro is NOT found to be particularly effective against the particular strain(s) tested or the most prevalent strains found in your area, and another is found to be very anti-bacterial in its action, the substantially more effective one will be substituted for the ineffective one. There are several substitutes available, with Leviquin being a commonly used one for renal infections.
It takes varying amounts of time to "grow" in the petri dish and to test for some effectiveness of individual drugs and depending on the time frames involved it may, or may not, produce results within the time frame available. Often, a broad spectrum antibiotic is initiated and does not need to be changed, even after testing is done, as it proves very effective. But, when considered pragmatic to do so, such testing can SOMETIMES result in a change in the originally prescribed antibiotic because the testing determines that the original broad spectrum antibiotic is not sufficiently effective, in that individual circumstance.
I hope this helps IF, as I SUSPECT, it is applicable to your situation. Don't hesitate to ask the Doctor if it is the case here. If he/she says it does NOT apply here, then ignore what I have communicated above, as I am a layman, not a physician! - John@newPCa.org (aka) az4peaks
Post Edited (az4peaks) : 9/30/2014 7:30:35 PM (GMT-6)