Xtandi / Zytiga trial

Charley -

How is it working for you so far? How are the SEs compared to Lupron?

- Allen

Houseboy,

Here ya go:
Serial blood-based analysis of AR-V7 in men with advanced prostate cancer

As you can see, it was a very small study, and it is only suggestive. But what is there to lose by re-challenging with Xtandi and/or Zytiga now?

Another very interesting prospect is the restoration of Xtandi sensitivity using a PD-L1 blocker (like Keytruda). You'd only be able to get that in a clinical trial, however.

- Allen

Hello Charley,
Looks like your last post was over five months ago. How are things? As the saying goes, welcome to the club that no one really wants to join.
You are going to get a lot of support and info here, stay with us and stay connected. It's good that you are seeking answers and looking at alternatives in your treatment. Of course try to find the best Oncology team that you can, and try to keep a positive outlook. It works for me. Interesting topic for your post, I will be following it. Can you post your "stats" a bit more fully in your profile. That will help us understand your situation more.

Houseboy,
I am very interested also in your treatments as I too have PCa with mets. I am curious about how many Cat scans you have been approved for and when they were done over the course of the past few years. Has insurance helped or limited their approvals.

Thanks much ,and as always great to have input and weblinks from Mr. Tall Allen
Keep the faith guys!
Dan in So Cal (with Cigna Ins)