Lupron question

I haven't been able to find an answer to this question. Does anyone know if there is a testosterone bounce on second or third shots? I just had my second shot a couple weeks ago and was just curious. Thought I might get an extra week of manhood in there somewhere

There shouldn't be any increase and hardly any variation. . The drug remains active many months after the shot duration and continues to suppress the T. If the T starts coming up while on the ADT drug it signals the drug isn't working.

What you are referring to is known as the testosterone flare. It can happen upon the first shot as the body reacts to the drug and initially makes more T before stopping T production. It usually happens in the first two weeks. Often casodex is given first to prevent the flare. Once you are castrate level the subsequent shots do not have the same effect.

In PCa generally the term bounce is used to describe the PSA increase then decrease in many men that use radiation only as the initial treatment. This often happens in the 18-36 month range and is thought to indicate a lot of PCa cells dying en masse.

Lupron causes microflares with each new shot. You will usually not notice that, just you cancer gets some additional food. Degarelix and some other drugs do not cause these microflares.