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New Trial Surgery vs. Radiation for HRPC
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Prostate Cancer
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Mrs.BD
Regular Member
Joined : Jul 2019
Posts : 93
Posted 2/3/2020 4:02 PM (GMT -5)
Hello everyone - I have been educating myself here on Healing Well since July. My husband was diagnosed with High Volume Metastatic Hormone Sensitive, moving to Hormone Resistant just recently. He's 58 years old. Very active, in great health except for the PC. We have to make a decision to either have radiation or surgery by tomorrow for a new clinical trial called S1802. Worried about
side effects. Since this is not standard of care (surgery or radiation), this is not something we have to do, as we will move on to standard of care - all of the drugs that are available. He's not the type to miss work or take any time off from work. Wishing our lives were back to normal.
Hopeful to figure out this forum as this is my first post.
All the best..
JNF
Veteran Member
Joined : Dec 2010
Posts : 6097
Posted 2/3/2020 4:39 PM (GMT -5)
I had radiation nine years ago and have done well with no negative treatment side effects. Generally surgery results in mor negative treatment side effects due to the inherent physical damage from surgery.
You are looking to debulk and limit the PCa coming from the mother ship. While not yet proven to help it certainly makes sense. My suggestion is that you choose the method that is least invasive and generally leaves less significant negative treatment side effects. That is radiation treatment.
DjinTonic
Veteran Member
Joined : Dec 2019
Posts : 2546
Posted 2/3/2020 4:40 PM (GMT -5)
Hi Mrs. BD and Welcome!
Here is a
link to the study
for those who want more details (see Arm II there)
Djin
InTheShop
Elite Member
Joined : Jan 2012
Posts : 11468
Posted 2/3/2020 4:45 PM (GMT -5)
Welcome to HW, sorry you need to be here.
as to side effects and working. Surgery will put him out of action for 2-3 weeks. It would be 6-8 weeks before he could lift anything over 5 pounds.
With radiation you have to go in for daily treatments which can be a scheduling problem. I managed to work for most of my 6 weeks, but by the end fatigue got me bad and I had to take a few days off.
Andrew
Mrs.BD
Regular Member
Joined : Jul 2019
Posts : 93
Posted 2/3/2020 4:56 PM (GMT -5)
Thank you - hopeful that hubby will chime in soon. His PSA jumped during the 5th out of 6 chemo treatments. We are very concerned and thankful for this site.
lapilot
Veteran Member
Joined : Nov 2012
Posts : 1026
Posted 2/3/2020 5:39 PM (GMT -5)
I had 39 treatments (IMRT/IGRT) radiation therapy. It was a none event for me. The radiotherapy was 5 days a week for 8 weeks. I schedule it for the late afternoon. I would get up 4:30am in the morning, drive to work and on the way home I stopped off at the hospital's radiation oncology center. I was usually in and out within 15 to 20 minutes.
I had zero side effects, no urinary or gastrointestinal problems at all, and I never had to changed my diet what so ever. I was able continued working without any problems.
When I completed the entire regime, and during my exit exam with the radiation oncologist I honestly asked him if the beam was actually on since I had zero problems. His response was yes, and he said most men have zero or very little side effects from this therapy.
BTW, it has been almost 5 years since radiotherapy, and 7 years since prostatectomy and I still don't have any ED issues, and only slight stress incontinence when lifting heavy equipment.
JNF
Veteran Member
Joined : Dec 2010
Posts : 6097
Posted 2/4/2020 12:06 PM (GMT -5)
Which form of radiation? Do you get to choose?
External beam traditional or SBRT? SBRT is usually only 5 or 6 procedures.
Brachytherapy? Permanent seeds one procedure and HDR either one or two
mattam
Veteran Member
Joined : Aug 2015
Posts : 4417
Posted 2/4/2020 12:13 PM (GMT -5)
I think there is something to the de-bulking theory. I'm glad a trial is underway to see if there is a worthwhile benefit.
Good luck to you!
Jesse W
New Member
Joined : Jan 2020
Posts : 8
Posted 2/4/2020 12:56 PM (GMT -5)
I am in this trial. I'm a gleason 10 with mets in bone and lymph nodes. I was diagnosed about
the same time as your husband. On Lupron and casodex and recently completed docetaxel. I chose radiation. I'm having external beam. It was my understanding external beam is the only type of radiation offered. I start Friday. I hope it helps!
mattam
Veteran Member
Joined : Aug 2015
Posts : 4417
Posted 2/4/2020 12:59 PM (GMT -5)
Welcome to the Forum Jesse. Please keep us updated on how things go.
Good luck ahead!
Mrs.BD
Regular Member
Joined : Jul 2019
Posts : 93
Posted 2/4/2020 2:50 PM (GMT -5)
Hi Jessie W - My husband is choosing radiation as well. I hope you both can talk - he has been looking for a guy with similar PC. I am going to assume that his radiation will start soon. Thank you!
Brooke
JNF
Veteran Member
Joined : Dec 2010
Posts : 6097
Posted 2/4/2020 4:37 PM (GMT -5)
Great that the decision has been made. Now you can prepare for it. Many of us have had radiation as primary treatment and can assist with our experiences.
Remember that this will be different than the men that had salvage radiation after surgery. In your case most all the radiation will be focussed on the prostate and thus the surrounding organs are little involved. Thus treatment side effects are generally diminished and dissipate within a few weeks after the last fraction.
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