tak06 said...
Thank you for that, looks like a another biopsy is unavoidable, feels like I'm playing with Russian roulette by prolonging this, time has probably come to seek treatment and cease AS., 11 plus yrs is fairly lengthy time that I've avoided treatment.
.
Another biopsy should give you valuable information not only about
any higher-grade lesions, but also the number and
location of your G6 lesions. I doubt that your docs will advise staying on AS if your disease become bilateral, you develop G7 lesions, or you have more than a couple of G6 lesions. As you know, a biopsy samples a minute amount of prostate tissue.
Not all men are cut out for AS and even some of those who are psychological OK with AS at the start, at some point decide they want to treat even if they can still are within their AS guidelines.
If you are on the fence after your next biopsy, I suggest having a Decipher or OncotypeDX test done on your biopsied tissue: results from the Decipher test found that 10% of men with
confirmed G6 disease nonetheless test high risk for developing lesions >6 and metastases within 10 years.
I do not mean to push you to treat: if, for example, your PSA is confirmed at a plateau of, say, 8, you have only one or two G6 lesions and they are unilateral, your genomic test comes back low risk for mets, and your docs think it OK, you might choose to remain on AS.
Djin
Post Edited (DjinTonic) : 10/20/2022 11:33:32 AM (GMT-7)