AHRQ: Comparing treatments for prostate cancer

The Agency for Healthcare Research and Quality released this document today but I can't find it on the internet. Some of the writers are my colleagues at ASCO and SWOG.

Document Title: Therapies for Clinically Localized Prostate Cancer: Update of a 2008 Systematic Review

Release Date: December 17, 2014

The document is highly technical and not patient facing. So it isn't for the newbie but it can be useful as well if you want to take the time to read it. I posted it at my website as this is a great comparison of the many treatment options out there for localized prostate cancer. It also lists various trials underway and the completion dates. A brief glance shows trials that are underway for PCa as well as the projected completion dates. Seeing one trial that concludes in 2040 shows me how entering a patient today in a G6 category has a very long life expectancy.

advancedpcatalk.freeforums.net/thread/237/ahrq-comparing-treatments-lcap

You are welcome sir.

But like I said, this is a very technical document. I expect few that can understand the nuances involved. Heck I have to ask questions as well. If anyone would like to ask questions about the various trials mentioned I do have that access to the primary investigators or their staff. Just let me know.

Here's a link to the study on AHRQ's website:
effectivehealthcare.ahrq.gov/search-for-guides-reviews-and-reports/?pageaction=displayproduct&productid=2023

Good stuff, thanks Tony.

Here's something that could help all levels of knowledge, though again some of the terms next to the acronyms may be foreign

Acronyms and Abbreviations
3D-CRT: three-dimensional conformal radiotherapy

95% CI: 95 percent confidence interval

ADT: androgen deprivation therapy

AJCC: American Joint Committee on Cancer

AHRQ: Agency for Healthcare Research and Quality (U.S. Department of Health and
Human Services)

ARR: absolute risk reduction

BT: brachytherapy

CAPRA: UCSF Cancer of the Prostate Risk Assessment

CT: computed tomography

DRE: digital rectal exam

EB-IGRT: external beam image-guided radiation therapy

EBRT: external beam radiation therapy

EORTC-QLQ: European Organization for Research and Treatment of Cancer Quality of Life Questionnaire

EPC: Evidence-based Practice Center

EPIC: Expanded Prostate Cancer Index Composite

ERSPC: European Randomized Study of Screening for Prostate Cancer

Gy: gray

HDR-EBRT: high dose–rate external beam radiation therapy

HDS: high dose rate

HIFU: high-intensity focused ultrasound

HR: hazard ratio

IGRT: image-guided radiation therapy

IMRT: intensity-modulated radiation therapy

IQR: interquartile range

KQ: Key Question

LDR: low dose rate

LHRH: luteinizing hormone–releasing hormone

LRP: laparoscopic radical prostatectomy

MRI: magnetic resonance imaging

NCCN: National Comprehensive Cancer Network

NIH: National Institutes of Health

OR: odds ratio

PCSM: prostate cancer–specific mortality

PICOTS: Population (patients), Intervention, Comparators, Outcomes, Timing, Setting

PIVOT: Prostate Cancer Intervention Versus Observation Trial

PLCO: Prostate, Lung, Colorectal, and Ovarian cancer screening trial

PSA: prostate-specific antigen

QOL: quality of life

RALRP: robotic-assisted laparoscopic radical prostatectomy

RARP: robot-assisted radical prostatectomy

RCT: randomized controlled trial

ROB: risk of bias

RP: radical prostatectomy

RPP: radical perineal prostatecto

RR: relative risk

RRP: radical retropubic prostatectomy

SEER: Surveillance Epidemiology and End Results (National Cancer Institute)

SF-36: Short Form-36

SOE: strength of evidence

SPCG-4: Scandinavian Prostate Cancer Group-4

TEP: Technical Expert Panel

TNM: T (tumor) N (lymph node) M (metastases) classification system (American Joint Committee on Cancer)

TOO: Task Order Officer

TRUS: transrectal ultrasound of the prostate

TURP: transurethral resection of the prostate

USPSTF: U.S. Preventive Services Task Force

WW: watchful waiting

Note: Acronyms and abbreviations used in appendix tables are defined within the tables in which they appear

Tony, I'm unlocking it now. Just let me know when you're done so I can re-lock.

Thanks,

Jim