Should I stop ADP or continue?

If you can add your signature, others can help you better.

Looking up your earlier posts, it seems you're a G8. That alone puts you in the higher risk category. Tough call on the ADT. Two years has been shown clearly superior in the context of radiation therapy, but I don't know about salvage radiation and so on. Our forum expert Tall Allen may have some useful links.

Here's one to a study by Dr. Nabid in 2013, describing his findings of the superiority of 2 years ADT over 6 months, but it's in the context of primary radiotherapy:
meetinglibrary.asco.org/content/114784-132

His presentation was never published as a paper, for some reason. You can't see the presentation there without some kind of log in or membership. You can see the abstract summary though.

And of course, there's the classic 2009 Bolla study, showing 3 years superior to 6 months of ADT. That's based on treatments long before the radiation therapies we have today, so it's controversial as to how it applies today. Again, it's specifically addressing ADT along with primary radiotherapy:
www.nejm.org/doi/full/10.1056/NEJMoa0810095

Your doctor can help you make a relative risk assessment. While longer term ADT provides some percentage of improved survivability, a low white blood cell count could be a bigger negative. There just aren't simple answers for a lot of this stuff.

The low WBC and low neutrophils could make me in life threatening danger. Is this true for ADT caused decrease of WBC?

I've never heard this effect of ADT either. Radiation can temporarily suppress WBC, but it should return to normal within a year if it was caused by that. Perhaps you may want a consult with a hematologist.

There is a medicine called Leukine that can increase your neutrophil count, but it carries very serious risks of its own. It is probably what they'd give you if you went into the ER with fever.

- Allen

You should do whatever TA tells you...

Hi all,

My PSA is now still very low <0.01 June 24/16) but my WBC is 1.6 and HgB is 113 only. I am scheduled to get the third Lupron shot two days after. My RO said it is depending on me to decide to stop the Lupron shot or not. I do not know what should I do. Please give me some advice.
Thanks a lot

Andy

I agree with TA. Don't rely on anyone except a qualified physician like an Immunologist. ADT is not great for the bones , which produce white blood cells so ADT is it helpful but you probably need ADT but you also need a good wbc count.
Bob

Sorry. I retract my statement re: ADT impact on production of white blood cells. ADT does impact your bones and joints which was what I was confusing with bone marrow where wbc's originate. However if you have a low wbc you need to find out why. I'm not sure why your uro said its up to you re:having more ADT. If your pca status dictates ADT then you should continue with it. Since you haven't posted a signature we can't say whether ADT is typically recommended for your situation. But you need to get your wbc up to the appropriate level. So visiting an appropriate physician is a must.
Bob

My RO is not fond of ADT either but he can't disputes that it has proven to be helpful so he has me on it for 13 months. I've read white papers that say one year is better than less than one year whereas much more than one year is controversial . So giving the least amount of effective dosage is what doctors usually do. Why over treat? On that basis you would benefit from a bit more ADT. But getting your wbc's to an acceptable level is just as if not more important.
Bob