I think I know where this is heading

Just got my 21 month uPSA results and it's .01. Three months ago it was .007, 6 months ago <.006. I know it's not a big move, but it's moving in the wrong direction. I guess with my pathology, I should have expected this, but like all of us, I was hoping I'd be the one that beat this outright with one treatment. It's very disheartening, to say the least.

So, I guess it's just waiting now for this to hit the magic number of around .03. Maybe I can get a good run before the next treatment(s).

Hang in there, brothers. I'll try to do the same.

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Age at Dx: 54 (DOB: 01/28/62)

08/31/15 PSA 2.5;
01/01/16 Urinary Frequency;
02/05/16 DRE Pos;
02/22/16 Biopsy;
02/26/16 Dx: 7-12 positive; (5) 3+3=6; (1) 3+4=7; (1) 4+3=7; T2B;
03/11/16 Bone Scan Neg;
03/23/16 CT Scan Neg;
03/31/16 Surgery Consult UPENN;
04/08/16 RT Consult/2nd Op Fox Chase CC upgrade to 4+4;
04/14/16 3TMRI "organ confined", EPE-, SV-, LN-;
06/01/16 DaVinci @ UPENN (Dr. D. Lee);
06/08/16 Catheter Out;
06/08/16 Post-Op Path: EPE+, Marg +, SV-, LN-, G7(4+3) (G4 80% - G3 20%), tumor vol 25%, T3a;
07/01/16 Start 5mg Daily Cialis, 20mg once a week on Friday's;
07/06/16 Decipher 0.56 (Average Risk), 5 Year Metastasis 7.6%, 10 Year PCa Specific Mortality 6.9%;
08/01/16 Penile rehab started (Pump);
08/31/16 uPSA <.006;
12/01/16 uPSA <.014 (? same lab);
01/30/17 Decipher GRID PORTOS: [Avg ADT Response (21%), Avg Docetaxel Sensitivity (56%),
Lower RT Response (45%), Avg Dasatinib sensitivity (38%), High Genomic Gleason Grade (81%),
High Metastasis Risk (70%), High Tumor Cell Proliferation (82%), Avg AR Activity (56%)];
03/01/17 uPSA <.006;
06/01/17 uPSA <.006;
09/01/17 uPSA <.006;
12/01/17 uPSA .007;
03/01/18 uPSA .010

Hi JayMot

I'm very sorry to see the upwards (albeit very slow) trajectory. GG had a 0.01 PSA late last year which returned to <0.01 at his subsequent test. So I guess it is possible for things to stabilise or at least move very slowly, but it would seem (to a lay person), that your pathology does indicate further tx might be required.

We are sending positive thoughts your way, for a very, VERY long remission before anything further is ever required.

Best of luck.
Jaybee&GG

Your final pathology could have been better. But stay positive. There are further treatments that can be curative. As others say, look for a good RO. Hang in there!

Losing the < sign has been the most difficult part of this journey (for me). When diagnosed....the goal posts were an immovable object that....once reached....meant victory.

The day I lost the < sign....was really the first time I felt the emotional effects of what it's like to be diagnosed with cancer. Real life seemed far away that day. For the first time...the goal posts were in a different location. It was discombobulating.

Suddenly....everyone has different opinions. And I'm the tie breaker.

You'll make the right calls when and if the need arises JayMot.

That jury could be deadlocked for years.

Take care man

J
It's easy to relate to your anxiety. But you are still in a good spot and untreated currently, correct? A course of Lupron would get it back down and your life wouldn't change much. I know you're probably not even close to that point yet but it's in your arsenal as well as radiation and other treatments. You've done the research so you know wher you stand. Like I said, I get the same feeling often but I say continue to enjoy your life as is. I hope your PSA drops back down to .006 but even if it doesn't you're on top of it.

Take care J

B