Harvard article - cancer cheats

ddyss said...
Nothing new but interesting to know

“ For example, researchers are now finding that non-steroidal inflammatory drugs can slow down the mutation rate and reduce the progression of esophageal cancer. “

Happy Friday!

Here is the article
/news.harvard.edu/gazette/story/2018/04/harvard-talk-envisions-path-to-containing-cancer/

Excellent news, especially if "proven" by RCTs. This should mean that all of us taking NSAIDs - which might be most of us- should do better in our fight against our cancers. But of course, even if that is proven, the result will have to be stout enough to overcome the SEs of NSAIDS, which are not exactly benign. (IOW, all cause mortality vs cancer specific mortality) Sometimes it seems like we fix one thing only to break another. But maybe it will be shown that the benefits outweigh the risk?



bjgp.org/content/bjgp/66/645/172.full.pdf

/www.medpagetoday.com/gastroenterology/pepticulcerdisease/1612

Somebody said...
ZARAGOZA, Spain, Aug. 26-Non-steroidal anti-inflammatory drugs (NSAIDs), including low-dose aspirin, are behind a third of all hospitalizations and deaths associated with GI bleeding, according to two Spanish studies.


The proportion of complications and deaths attributed to NSAIDs and aspirin use was 36.3%, said Angel Lanas, M.D., of the Hospital Clinico Zaragoza. A third of these cases were attributed to low-dose aspirin.

Billybob , I’m not jumping in the nsaid’s bandwagon yet except that now when I do take them for pain, I will know that maybe they are helping me in more ways than what I need them for.

The punch line of the article though was

“
Most exciting, Aktipis said, is a new form of adaptive therapy that has been found to control cancers in mice and has seen promising trials in humans. In this case, tumors are treated with drugs only when they are actively growing and are otherwise left alone; this approach keeps drug-resistant cells from taking over.“

Post Edited (ddyss) : 4/7/2018 7:22:52 AM (GMT-6)