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Trimix not working, need suggestions

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Prostate Cancer
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Posted 5/20/2018 6:11 PM (GMT -5)
History:
60 year old male
Never had prostate or back surgery
Had scope done March, enlarged prostate but no cancer
Prescribed flowmax and happy with results
Highest weight 350lbs August 2017
August 2017 respiratory issues and steroids put me over the edge became diabetic
Began weight loss journey August 2017, reduced weight with diet and exercise to 285lbs. Still losing and working hard at it with HIIT and counting calories with healthier choices, goal weight 250
Non smoker
Social drinker! 1-2 mixed drinks a month
Used viagra since 42, 50mg worked fine, over years increased to 100 mg, stopped working many years ago,
Tried cialis, better results with viagra
Tried ED Vac pump, got erection but lost immediately when removing pump
Used various rings and adjustable restriction devices. Still lost er reaction within 5 mins
Urologist prescribed trimix and went to his office was shown how to inject. Injected with wt units, cave a semi erection in 15 minutes. He checked said I could increase dosage to 50 units or use restriction device on base of penis. Semi last 2 hours
Home use tried 50 units, slight results. Not enough for intercourse
Tried again 60 units, not enough for intercourse. Both times at home erection would come, go, walking around it would come back and then go again. Anytime there was an erection it was not enough for intercourse. It could possibly work with a ring but prefer not to use one.
Questions:
Am I doing something wrong?
Do I need to increase dosage some more?
Do I need a stronger mix of trimix? Current prescription is

Papavarine 30mg
Alprostadil 20mg
Phentolarmibe 1mg

Thank you I look forward to the groups help and suggestions
Posted 5/20/2018 8:07 PM (GMT -5)
You might want to check out the the website, franktalk.org. Lots more information there for guys in your position. We mostly talk about prostate cancer and it's effects. You might need a higher dose or you might consider an implant.

Andrew
Posted 5/20/2018 8:19 PM (GMT -5)
Thank you and good luck to you
Posted 5/21/2018 10:15 AM (GMT -5)
Some of what you describe sounds like you may have one or both of a related pair of problems -- arterial insufficiency or venous leak. They are sort of the same thing: blood leaks out faster than it comes in. If too little come in it is arterial insufficiency, if too much leaks out its a venous leak. Erections that are better when you stand up but go away when you lay down are fairly typical of that sort of problem. I think diabetes is one of the possible causes of this sort of problem.

We've had members who saw their venous leak improve over time using large doses of stronger mixes of trimix, so that's worth trying with your doctors approval and help. Men with venous leaks need more of the drugs since the blood that leaks out carries away the meds. Men with good venocclusion (the opposite of a venous leak) need to be careful with trimix because too much will send them to the emergency room with one of those four-hour erections they talk about in Viagra ads.

I spent about three years with trimix three times a week, trying somewhat to work past a venous leak but mostly trying not to shrivel. Eventually I had an implant installed with which I am reasonably happy.

Do check in with FrankTalk.org. They have more discussion of such things than we do here.
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