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New Diagnostic Test under Investigation

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Prostate Cancer
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Posted 6/27/2019 8:07 AM (GMT -5)
Here’s a study on a new genetic urine test that seems to do a good job both diagnosing and sorting out men who need treatment vs less aggressive cases. Still in the investigational phase

https://onlinelibrary.wiley.com/doi/full/10.1111/bju.14811

Somebody said...
Conclusion

Urine‐derived EV‐RNA can provide diagnostic information on aggressive prostate cancer prior to biopsy, and prognostic information for men on AS. PUR represents a new and versatile biomarker that could result in substantial alterations to current treatment of patients with prostate cancer.

Here’s a plain English article that reports on this new development...
https://www.healthline.com/health-news/urine-test-may-make-prostate-cancer-diagnosis-easier

It’s great to see new advances popping up on a regular basis in the diagnosis and treatment of PCa. It bodes well for our sons .
Posted 6/27/2019 8:44 AM (GMT -5)
I consult with one of the authors listed, Dr. Martin Sanda, as part of my AS program. I'm also part of the PASS Research Study that Emory is involved in. I'm glad that my post-DRE urine samples are being put to good use.
Posted 6/27/2019 9:47 AM (GMT -5)
YAY! more tests.
Posted 6/27/2019 9:47 AM (GMT -5)
At first read, this really does look like the kind of diagnostic tool that has been needed. If it proves out, it may be part of the answer to really identify those who need treatment vs those who are indolent.
Posted 6/27/2019 10:34 AM (GMT -5)
Arguably the ultimate goal of PCa diagnosis and treatment is: Diagnose with a urine test, treat with a pill.

If this new test holds up, maybe we are getting to the halfway point of realizing that goal.
Posted 6/27/2019 11:33 AM (GMT -5)
Like I said, it would be great for our sons. And anyone else that comes along as a newbie. Let’s hope it pans out to be real.
Posted 7/10/2019 11:52 AM (GMT -5)
Sounds very similar to SelectMDX (https://prostatemdx.org/prostate-biomarkers), which has a 98% chance of predicting high or low risk PCa. A poster on another forum had the SelectMDX test but was later found to have high risk PCa. There is that 2% that the test misses. If the test is cheap enough I will get it done, but the results will be weighed in conjunction with other diagnostics.
Posted 7/10/2019 12:42 PM (GMT -5)
Odd, never had a urine test in the past year that I recall. Always gets waived in Uro's office since I don't have a urination or bladder issue to deal with. In fact, my regular doctor has not taken a urine test in years while it seemed a regular part of my youth. Must be that blood tests suffice for most things?
Posted 7/10/2019 1:18 PM (GMT -5)
I do know that kidney function and diabetes can be monitored by blood testing. Like you, I have not have a urine test in several years.
Posted 7/10/2019 3:16 PM (GMT -5)
I've been giving a urine sample every uro visit so practically at least twice a year. I also have been giving a post-DRE urine sample twice a year as part of the PASS study I'm in.
Posted 7/11/2019 8:08 PM (GMT -5)

ASAdvocate said...
I do know that kidney function and diabetes can be monitored by blood testing. Like you, I have not have a urine test in several years.

Liver functions are checked by blood tests as well on yearly physicals
Hep B and Hep C too
Posted 7/13/2019 8:42 AM (GMT -5)
so I've been thinking about this: If the test has been under investigation, when will it be arrested and will it be charged with?
Posted 7/13/2019 9:32 AM (GMT -5)
I have a urine sample at each of my four urologists visit each year and every time I go to my GP. Standard operating procedure for each of them.
Posted 7/13/2019 2:29 PM (GMT -5)

JNF said...
I have a urine sample at each of my four urologists visit each year and every time I go to my GP. Standard operating procedure for each of them.

4 urologists....all at the same time??? WOW
Posted 7/13/2019 2:34 PM (GMT -5)
JNF - I always ask at the Uro’s office since they automatically want to hand me a cup at check in, even when just getting a PSA. They then look at why I am there and say I don’t need to after all. Never had one yet after the first visit.
Posted 7/13/2019 3:13 PM (GMT -5)
Gary, one urologist and four visits per year. Sorry for the inaccuracy.

Mumbo, urine specimen for my urologist is routine just as the obligatory listening to the heart at my primary care physician. Always takes a listen no matter why I visit.
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