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4 years post LDR brachytherapy psa increase

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Posted 10/2/2019 8:38 PM (GMT -5)
It's been 4 years since my lose dose brachytherapy and all has been great. Last October I had my lowest psa at 3years it was .30. 6 months later it went up to .40. Now my 4 year results are .60. I have my typical bounce at 2 year point. So it looks like I'm heading for a relapse even though everything else seem to be in order. Anyone else still hovering at .6 to 1.0 mark at 4 years. My doc wants me below .40 now and even though I was at one point it seems like that's not to be.
Posted 10/3/2019 8:47 AM (GMT -5)
So your space is up to 2.30 before a technical recurrence. However, the trend is not favorable so far. Your nadir was favorable as it was under 0.50. What was your initial dx in terms of PSA, Gleason and number of positive cores? Did you also have external beam treatment? Has you doc discussed any scans as the next step?
Posted 10/3/2019 9:05 AM (GMT -5)
Sorry I didn't post all my history.
Dx June 15-t2b G6 8/12 cores +. Had one eligard in July '15 and brachytherapy Oct.'15....psa dropped incrementally. PSA was 0.3 last Oct. then 0.4 in April and now 0.6. I never had ebrt. I was afraid of this being the trend towards failure and it looks that way.
Posted 10/3/2019 9:12 AM (GMT -5)
Sorry can't seem to update my signature with current info.
Posted 10/3/2019 9:16 AM (GMT -5)
It might be and you might be heading for more treatment, but you'll need more tests to know for sure.

A retest in a couple of months would be in order to confirm/deny the trend.

sadly, I think you're stuck in wait and see mode.
Posted 10/3/2019 12:51 PM (GMT -5)
Tall, it's possible that you are still bouncing and have not reached nadir. While I didn't seem to bounce after my LDR Brachy, it took me 6 years to reach nadir. Actually, I may have bounced but since I was only doing annual PSA tests the bounces may have happened and I never knew about them...

In any case, it's probably appropriate that you are a bit worried and I would suggest that you re-do your PSA tests quarterly to stay on top of this. You also might discuss an infection with your doc and treat accordingly. You still have a prostate and it's not totally unknown for some infection to occur and affect PSA scores.

In any case you are still far from official recurrence so watch it carefully and hope for the best.

Jim
Posted 10/3/2019 5:40 PM (GMT -5)
It also took me a few years to reach nadir - hope this is the same for you.
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