RANT: UC Ulcers Diarrhea Caused?

I put the question mark after the title bc I'm asking, not making a statement and rather ticked off so read at your own risk.

Short version: last week had thyroid tested for hyper. Hot for past 3 months, shakes, losing weight (not eating bc throat closing) yet I didnt have any UC symps and no fever. Odd. Results neg but WBC came back very high. Appears its just a sore throat infection (where my thyroid is). Wow, nothing like feeling like a hypochondriac on that one. Sometimes is better to not overthink. Whatever.

Anyway, been in remission for over a year blah blah and I was faced to either take antibiotic or slowly let my throat close up. Um, gonna have to take it on the chin with this one. Yay. So doc and I decided to put me on Azi. Took my first 2 pill starter roughly 3:30 pm yesterday in the hospital parking lot. Figured I'd stay close in case I choked (I'm really not kidding about the throat closing thing)

Here's where it gets fun. Had a solid BM about an hour later. about 2 hours after that had a mushy with some gas. Another mushy then bang got the big D before bedtime. Great. Threw some extra probots in me n went to bed. Woke up 3 times with D and before work. Made thru the morning ok with just cramping and gurgles. Decided to take rest of day off and this afternoon.. blood. ***! I can't even use my magic to trick my immune system to chilling out so I can self-regulate faster or consequently deal with a closed esophagus. Catch 22 here.

I repeat.. ***!!! Never in 17 years have I got hit this fast this hard.

So this is what I think and maybe its just bc I'm PO'ed and venting up a storm here, idk. Diarrhea is what brings the ulcers not the immune system. I cannot fathom that my immune system and "bad"genes suddenly started attacking my guts when I've had an elevated immune system for 3 friggin months. It doesn't matter what gave D to you.. pathogens, diet, stress, antibiotics, planet alignment, neighbor domestic down the street, northeasterly wind currents..
The cold truth is that if you have D and if you can't get it under control, you WILL flare.

The deciding factor here FOR ME seems that the delicate balance of intestinal microflora has been upset. Now I'm bleeding bad tonight. ***. I'm throwing the gene thing out the stinking door along with his friend diet. It's nice outside now so they won't freeze to death. Maybe theres some truth to not being able to self-align due kras blah blah but no one in my blood related family has it but me.

Stress and antibiotics brought this one on, I'm 100% positive. Diet makes it worse but unless you are enzyme deficient or eating a bunch of no no's or known allergens it only makes existing UC more complicated. Even then with the imbalance of microflora it can be labelled a trigger.

So what has sliced me up so bad in 24 hours? I'll tell you my theory. Now that I've officially flushed my hard earned bacterial balance down the crapper, something in there (toxins, candida, virus, bad bacteria whatever) has poked holes in my mucosal lining and survived the D onslaught and Azi. I don't have any mysterious lesions that are bleeding anywhere else on my body..

Conclusion to this rant and if you have made it this far I'm amazed: STRESS and antibiotics causes D and D creates an environment for ulcers, not my diet or genes. So therefore whatever the cause may initially be of the diarrhea, it is the balance of intestinal microflora that PROTECTS us against the ulcers.

Looks like instead of researching UC for awhile I get to experience it too. ugh.

Thanks for the support. This too shall pass. I was all jacked up for a thyroid issue and even knew what I was going to start taking for it. But nope I ended up on a Z pac cycle caught with my pants down on that one. Pun intended.

Ramping up your probo intake was a wise idea. I wish I had done the same instead of putting all my eggs in one basket on this thyroid thing.
I'm beginning to think the probo's are more essential to us than we give them credit as far as protecting us and keeping things balanced. A form of shield perhaps.

I had a belly bug a few weeks ago as well. Vomit and D. I got the resulting D under control after 4 days or so. No blood and almost instant solids again. I think some of the friendly bacteria colonize the lining of the intestine and survive certain lengths of D by "hanging on" thru the bulk of the flush, as long as pH gradients and certain agents do not kill them. However, I think the azi has targeted some of my colonized friendlies in there and some azi resistant bad stuff has replaced the bare spots.

I just can't understand how fast I could be bleeding. Doc says my immune system been switched on high for about 3 months. I cant believe I had a throat infection for 3 months either. So the only thing I can think of is its the azi messing with my bacteria bc nothing else changed.

uc warrior: I'm not sure i understood all of your theories, but the one thing that came through which i think is something we all feel is:  when you are in remission and doing well and then BAM, hit with a flare.  It is the most dissapointing, frustrating feeling.  I am as perplexed as you with how these flares can come out of nowhere and then all the trial and error we go through to find out what makes us feel better. I am also an optimist, if you up your oral meds, increase your rectal meds, increase your probiotics, eat the most mild  non-infammatory foods then hopefully you can get to where you where.

Bananagirl: as far as antibiotics, before you take them make sure what you have is bacterial not viral,if its viral then antibiotics are not going to do a thing.

i have never seen any improvement in my uc symptoms from probiotics.  besides my lialda and rowasa, the most helpful thing i have done where i saw an immediate decrease in symptoms was to give up caffiene. 

Thanks everyone. Well, somehow I'm back to forming semi-solids again. Specks of blood this afternoon but I guess I made it thru the bulk of the storm. One BM today. Crazy *&$t, I know.. So now I upped my probots today n last night and only ate some saltines and applesauce. 2 lbs of carrots and 2 lbs of celery juice later I came out the other end with the other end ending in something other way. say that one real fast.

Talked to doc over lunch break and we have come up with an infectious colitis theory bc it hit so fast. No more z pac for me. Shucks I was really hoping it was going to go panco on me again and put me in the hospital. -sarcasm

Thyroid and all other hormones came out peachy. No STDs. Yet still Fever, high WBC and Ca levels, tremors and weight loss, night sweats, coughing and general fatigue. The Azi was a nightmare of which I stopped taking. If my throat closes up I'd rather jam a pen in my neck for an on the spot tracheotomy and drive to hosp than go panco again (that's what that mini flare was feeling like). I'm not kidding. There was an earlier post about insanity, yeah I guess after a certain period of time you do become somewhat insane..

So the problem remains.. how did a throat infection make me lose almost 30 lbs in 3 months? drumroll please..

It's not bacterial! Getting my basement checked tomorrow bc me n the doc think its some form of mycotoxicosis. He gets a kick out of all my ideas and can't wait until I get my doctorate. I think outside the bozx so much I'm not even sure what is really inside. I'll prolly get sued after my 3rd or 4th patient.. hahaha. mark that as my UC theory #one million and forty two.

Strangely this theory makes more sense than all the others. Why?

I didnt get IBD until we moved into this house. 6 months after to be exact, right before college. My dad had IBS issues while living here but never developed IBD. He had AB blood type though and he never ever got sick. Raw hamburger, moldy bread, stale beer.. he was a machine.

If a fungus colonizes a portion of your intestine what will it do? Molds are crazy good at killing bacteria. Hmm, need probot supps anyone? I'm not even hinting at candida, I'm talking stuff like A. fumigatus, flavus, the n word, versicolor, S. Chartarum C. Globosum, the list goes on and on. I wish I never took microbiology now. Stuff that can poke holes in your mucosa and travel your bloodstream. Yay.

Any of these fungi can create the environment for other fungi. Candida is opportunistic and if the immune system is busy attacking something else Candida slips in. Thats y we respond well to antifungals and probiotics and theres so much talk about candida.

If I find out I've had infectious colitis for 17 years that has gone rectal to panco and everything in between I'm going to pass out. Really I'm going to pass out.